Phyllanthin - Moligand™,≥99% , CAS No.10351-88-9

CAS: 10351-88-9 Cat. No.: P1453180 Molecular Weight: 418.52

GRADE & PURITY Moligand™, ≥99%

Synonyms

PHYLLANTHIN | PHOSPHO-L-SERINE,O-(RG) | 1,1'-[(2S,3S)-2,3-Bis(methoxymethyl)-1,4-butanediyl]bis[3,4-dimethoxybenzene] | NSC619043 | 3,3',4,4',9,9'-HexaMethoxylignan | Tetra-O-Methylsecoisolariciresinol | (2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Overview

Phyllanthin is an effective oral anticancer agent. Phyllanthin inhibits MOLT-4 cell viability, increases apoptosis , inhibits cell migration and invasion. Phyllanthin exerts anti-fibrotic effects by down-regulating TGF signaling pathway via ALK5 and Smad2/3. Phyllanthin also has anti-inflammatory and antibacterial properties.

Specifications

Synonyms

PHYLLANTHIN | PHOSPHO-L-SERINE, O-(RG) | 1, 1'-[(2S, 3S)-2, 3-Bis(methoxymethyl)-1, 4-butanediyl]bis[3, 4-dimethoxybenzene] | NSC619043 | 3, 3', 4, 4', 9, 9'-HexaMethoxylignan | Tetra-O-Methylsecoisolariciresinol | (2S, 3S)-(+)-1, 4-Dimethoxy-2, 3-diveratrylbutane

Specifications & Purity

Moligand™, ≥99%

Storage

Store at 2-8°C, Protected from light

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥99%

Names and Identifiers

• Canonical Smiles: COCC(CC1=CC(=C(C=C1)OC)OC)C(CC2=CC(=C(C=C2)OC)OC)COC
• IUPAC Name: 4-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene
• InChIKey: KFLQGJQSLUYUBF-WOJBJXKFSA-N
• INCHI: 1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1
• Isomeric SMILES: COC[C@@H](CC1=CC(=C(C=C1)OC)OC)[C@H](CC2=CC(=C(C=C2)OC)OC)COC
• Molecular Weight: 418.52

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lignans, neolignans and related compounds
    • Class Dibenzylbutane lignans

• Kingdom: Organic compounds
• Superclass: Lignans, neolignans and related compounds
• Class: Dibenzylbutane lignans
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Dibenzylbutane lignans
• Alternative Parents: Dimethoxybenzenes Phenoxy compounds Anisoles Alkyl aryl ethers Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Dibenzylbutane lignan skeleton - Dimethoxybenzene - O-dimethoxybenzene - Anisole - Phenoxy compound - Phenol ether - Methoxybenzene - Alkyl aryl ether - Benzenoid - Monocyclic benzene moiety - Ether - Dialkyl ether - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as dibenzylbutane lignans. These are lignan compounds containing a 2,3-dibenzylbutane moiety.
• External Descriptors: Lignans

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: light sensitive