Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Propofol potently and directly activates GABA A receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic.
| ALogP | 3.8 |
|---|
| Isomeric SMILES | CC(C)C1=C(C(=CC=C1)C(C)C)O |
|---|---|
| WGK Germany | 3 |
| RTECS | SL0810000 |
| UN Number | 2810 |
| Molecular Weight | 178.27 |
| Reaxy-Rn | 1866484 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1866484&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Freezing Point(°C) | 18 °C |
|---|---|
| Refractive Index | 1.514 |
| Flash Point(°F) | 235.4 °F |
| Flash Point(°C) | 113 °C |
| Boil Point(°C) | 256°C |
| Melt Point(°C) | 18°C |
| 1. Shuai Liu, Keming Zheng, Yilin Jiang, Susu Gai, Bohan Li, Dehai Li, Shuang Yang, Zhihua Lv. (2023) Biotransformation of Penindolone, an Influenza A Virus Inhibitor. MOLECULES, 28 (3): (1479). [PMID:36771146] [10.3390/molecules28031479] |
| 2. Ma Zijian, Ma Yang, Cao Xuefeng, Zhang Yunpeng, Song Tieying. (2022) Avenanthramide-C Activates Nrf2/ARE Pathway and Inhibiting Ferroptosis Pathway to Improve Cognitive Dysfunction in Aging Rats. NEUROCHEMICAL RESEARCH, 48 (2): (393-403). [PMID:36222956] [10.1007/s11064-022-03754-2] |
| 3. Jiang Tianze, Xie Laozhi, Zhou Songlei, Liu Yipu, Huang Yukun, Mei Ni, Ma Fenfen, Gong Jingru, Gao Xiaoling, Chen Jun. (2022) Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-21). [PMID:36045429] [10.1186/s12951-022-01592-6] |
| 4. Yujie Tang, Shiyin Zhao, Zemin Peng, Zhen Li, Liang Chen, Pei Gan. (2021) Cu2O nanoparticles anchored on carbon for the efficient removal of propofol from operating room wastewater via peroxymonosulfate activation: efficiency, mechanism, and pathway. RSC Advances, 11 (34): (20983-20991). [PMID:35479351] [10.1039/D1RA03049C] |
| 5. Bai Z. M., Li X. F., Yang Y., Yang Y. F., Lv D. R., Tang L. L.. (2021) Propofol inhibited gastric cancer proliferation via the hsa-miR-328-3p/STAT3 pathway. Clinical & Translational Oncology, 23 (9): (1866-1873). [PMID:33772723] [10.1007/s12094-021-02595-9] |
| 6. Zifei Qin, Peile Wang, Shuyi Duan, Xiaoying Wan, Han Xing, Jing Yang, Xiaojian Zhang, Zhihong Yao, Xinsheng Yao. (2021) Potential Determinants for Metabolic Fates and Inhibitory Effects of Isobavachalcone Involving in Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Efflux Transporters. JOURNAL OF PHARMACEUTICAL SCIENCES, [PMID:33610566] [10.1016/j.xphs.2021.02.013] |
| 7. Xinqiang Li, Han Xing, Zifei Qin, Jing Yang, Peile Wang, Xiaojian Zhang, Zhihong Yao, Xinsheng Yao. (2020) Potential metabolism determinants and drug–drug interactions of a natural flavanone bavachinin. RSC Advances, 10 (58): (35141-35152). [PMID:35515695] [10.1039/D0RA06961B] |
| 8. Xing Han, Yang Jing, Ren Kaidi, Qin Zifei, Wang Peile, Zhang Xiaojian, Yao Zhihong, Gonzalez Frank J, Yao Xinsheng. (2020) Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu-gu-zhi) and its potential inhibition against human cytochrome P450s and UDP-glucuronosyltransferases. JOURNAL OF PHARMACY AND PHARMACOLOGY, 72 (12): (1865-1878). [PMID:32750744] [10.1111/jphp.13337] |
| 9. Li Yang, Xu Chunxia, Xu Jinjin, Qin Zifei, Li Shishi, Hu Liufang, Yao Zhihong, Gonzalez Frank J, Yao Xinsheng. (2020) Characterization of metabolic activity, isozyme contribution and species differences of bavachin, and identification of efflux transporters for bavachin-O-glucuronide in HeLa1A1 cells. JOURNAL OF PHARMACY AND PHARMACOLOGY, 72 (12): (1771-1786). [PMID:32648321] [10.1111/jphp.13324] |
| 10. Qin Zifei, Jia Mengmeng, Yang Jing, Xing Han, Yin Zhao, Yao Zhihong, Zhang Xiaojian, Yao Xinsheng. (2020) Multiple circulating alkaloids and saponins from intravenous Kang-Ai injection inhibit human cytochrome P450 and UDP-glucuronosyltransferase isozymes: potential drug–drug interactions. Chinese Medicine, 15 (1): (1-18). [PMID:32655683] [10.1186/s13020-020-00349-3] |
| 11. Yang Li, Jinjin Xu, Chunxia Xu, Zifei Qin, Shishi Li, Liufang Hu, Zhihong Yao, Frank J. Gonzalez, Xinsheng Yao. (2020) Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells. XENOBIOTICA, [PMID:32116078] [10.1080/00498254.2020.1732496] |
| 12. Li Wang, Xiaodan Hong, Zhihong Yao, Yi Dai, Guoping Zhao, Zifei Qin, Baojian Wu, Frank J. Gonzalez, Xinsheng Yao. (2018) Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes. XENOBIOTICA, [PMID:28443723] [10.1080/00498254.2017.1323139] |
| 13. Zhihong Yao, Shishi Li, Zifei Qin, Xiaodan Hong, Yi Dai, Baojian Wu, Wencai Ye, Frank J. Gonzalez, Xinsheng Yao. (2017) Characterization of human UDP-glucuronosyltransferases responsible for glucuronidation and inhibition of norbakuchinic acid, a primary metabolite of hepatotoxicity and nephrotoxicity component bakuchiol in Psoralea corylifolia L.. RSC Advances, 7 (83): (52661-52671). [PMID:] [10.1039/C7RA10376J] |
| 14. Shouhui Chen, Dan Zhou, Qinghao Xiong, Yinan Yang, Mingyang Zhang, Shoulin Chen. (2024) Electrochemical sensors based on composites of porous Fe3O4/C and carbon black for sensitive and rapid detection of propofol. Analytical Methods, [PMID:39552219] [10.1039/D4AY01280A] |
| 15. Nan Jiang, Xianxu Li, Guangcai Zhang, Zhuran Hu, Xiaoteng Fan, Mingsheng Li, Huimin Sun, Xianqiang Yin, Jun Wang. (2024) Environmentally Relevant Concentrations of Propofol-Induced Metabolic Dysfunction in Zebrafish: Mechanistic Insights into Integrated Hepatic Transcriptomic and Metabolomic Analyses. ACS ES&T Water, [PMID:] [10.1021/acsestwater.3c00834] |
| 16. Liang Shan-Yan, Xu Xiao-Min, Wang Peng, Ye Ming-Li, Zhang Shui-Feng, Zhao Yong-Gang. (2024) Fast Determination of Propofol in Human Plasma Using C18-Functionalized Magnetic Nanomaterials Followed by Supercritical Fluid Chromatography. JOURNAL OF CHROMATOGRAPHIC SCIENCE, [PMID:39436312] [10.1093/chromsci/bmae053] |
| 17. Chunli Qi, Jiangnan Fu, Huinan Zhao, Huijie Xing, Dong Dong, Baojian Wu. (2018) Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin. XENOBIOTICA, [PMID:29436891] [10.1080/00498254.2018.1440657] |
| 18. Dan Wang, Hui Sun, Kerong Hai, Ningkang Li, Yang Gu, Zengrui Ma. (2025) Propofol alleviates traumatic brain injury through regulating Th17/Treg balance by activation of the AMPK/SIRT1 pathway. TOXICOLOGY MECHANISMS AND METHODS, [PMID:40172234] [10.1080/15376516.2025.2481893] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
