10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
PROTAC AR-V7 degrader-1 (Compound 6) is a potent, orally bioavailable and selective AR-V7 degrader with the DC 50 of 0.32 µM by recruiting VHL E3 ligase to Androgen receptor (AR) DNA binding domain (DBD) binder. PROTAC AR-V7 degrader-1 exhibits activity against 22Rv1 cell-line expressing AR-V7 with the EC 50 of 0.88 µM
IC50& Target:VHL
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
PROTAC AR-V7 degrader-1 (Compound 6) is a potent, orallyxa0bioavailable and selective AR-V7 degrader with the DC 50 of 0.32xa0µM by recruiting VHL E3xa0ligasexa0to Androgen receptorxa0(AR) DNA bindingxa0domain (DBD) binder. PROTAC AR-V7 degrader-1 exhibit
Storage
Protected from light, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
Molecular Weight
789.02
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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