PY159 (anti-TREM1) - Primärer Antikörper, specific to TREM1, Human IgG1

Cat. No.: Ab190130

QUALITÄT & REINHEIT Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Mensch

Reactive species

Mensch

Isotype

Human IgG1

Conjugation

Unconjugated

Übersicht

PY159 (anti-TREM1) is a humanized agonistic monoclonal antibody targeting triggering receptor expressed on myeloid cells 1 (TREM1), with potential immunomodulating and antineoplastic activities.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg
Protein Function
Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.

Spezifikationen

Product Name

PY159 (anti-TREM1) - Primärer Antikörper, specific to TREM1, Human IgG1

Synonyme

CD354 antibody | OTTMUSP00000018206 antibody | TREM 1 antibody | TREM-1 antibody | TREM1 antibody | TREM1_HUMAN antibody | Triggering receptor expressed on monocytes 1 antibody | Triggering receptor expressed on myeloid cells 1 antibody | Triggering recep

Spezifikationen & Reinheit

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Wirtsspezies

Mensch

Spezifität

TREM1

Konjugation

Unconjugated

Note

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Isotyp

Human IgG1

Lichterketten-Typ

kappa

SDS-PAGE

143.66 kDa

Verfahren zur Reinigung

Protein A purified

Konzentration

See COA

Product Line

Biologische Produkte

Lagerung und Versand

Storage

Store at -80°C,Avoid repeated freezing and thawing

Verschickt in

Dry ice packs + Cold packs

Stabilität und Lagerung

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

ELISA: PY159 (anti-TREM1) (Ab190130)

PY159 (anti-TREM1) (Ab190130) - ELISA
Immobilized Human TREM1/CD354, Fc Tag at 2.0 μg/mL can bind PY159 (anti-TREM1) (Ab190130) with the EC50 of 9.661 ng/mL.

SEC: PY159 (anti-TREM1) (Ab190130)

PY159 (anti-TREM1) (Ab190130) - SEC
The purity of PY159 (anti-TREM1) (Ab190130) is more than 95% verified by HPLC.

Zugehörige Ziele (menschlich)

TREM1 Tbio Triggering receptor expressed on myeloid cells 1 (0 Activities)

Discover Target: TREM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Wirkungsmechanismen

Häufig gestellte Fragen

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (PY159 (anti-TREM1)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.