≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product Describtion:
Diacylglycerol Kinase Inhibitor I prevents the formation of foreign body giant cell (FBGC). It inhibits the phosphorylation of diacylglycerol to phosphatidic acid. Diacylglycerol Kinase Inhibitor I functions as a serotonin (5-HT) receptor (5-HTR) antagonist. It stimulates apoptosis and autophagy in neuronal cell line NG108-15.
Product application:
Diacylglycerol Kinase Inhibitor I has been used as an inhibitor to study suppression of T cell function using advanced generation human CAR (chimeric antigen receptors) T cells.
| Canonical Smiles | CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=CC=C4)C5=CC=C(C=C5)F)CC3 |
|---|---|
| IUPAC Name | 6-[2-[4-[(4-fluorophenyl)-phenylmethylidene]piperidin-1-yl]ethyl]-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one |
| InChIKey | MFVJXLPANKSLLD-UHFFFAOYSA-N |
| INCHI | 1S/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10,17-18H,11-16H2,1H3 |
| Isomeric SMILES | CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=CC=C4)C5=CC=C(C=C5)F)CC3 |
| WGK Germany | 3 |
| PubChem CID | 3012 |
| Molecular Weight | 459.58 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Diphenylmethanes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Diphenylmethanes |
| Alternative Parents | Pyrimidones Fluorobenzenes Aralkylamines Piperidines Aryl fluorides Thiazoles Heteroaromatic compounds Trialkylamines Lactams Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organofluorides Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Diphenylmethane - Fluorobenzene - Halobenzene - Pyrimidone - Aralkylamine - Aryl fluoride - Aryl halide - Piperidine - Pyrimidine - Thiazole - Heteroaromatic compound - Azole - Tertiary aliphatic amine - Tertiary amine - Lactam - Azacycle - Organoheterocyclic compound - Organic oxide - Organofluoride - Organohalogen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Amine - Hydrocarbon derivative - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E2312575 | Certificate of Analysis | Feb 05, 2026 | R288294 |
| E2312585 | Certificate of Analysis | Feb 05, 2026 | R288294 |
| E2312589 | Certificate of Analysis | Feb 05, 2026 | R288294 |
| E2312601 | Certificate of Analysis | Feb 05, 2026 | R288294 |
| E2312602 | Certificate of Analysis | Feb 05, 2026 | R288294 |
| K2521099 | Certificate of Analysis | Apr 25, 2023 | R288294 |
| K2521135 | Certificate of Analysis | Apr 25, 2023 | R288294 |
| Solubility | Solvent:ethanol, Max Conc. mg/mL: 9.19, Max Conc. mM: 20; Solvent:DMSO, Max Conc. mg/mL: 22.98, Max Conc. mM: 50 |
|---|---|
| Molecular Weight | 459.600 g/mol |
| XLogP3 | 5.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Exact Mass | 459.178 Da |
| Monoisotopic Mass | 459.178 Da |
| Topological Polar Surface Area | 61.200 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 868.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
