GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.≥95%(SDS-PAGE)
Accession #
Q14116
Protein Tag
No tag
Expression system
E. coli
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC50 of 30.0 ng/mL. Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC50 of 400.2 ng/mL.
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The com
Bioactivity
Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC50 of 30.0 ng/mL. Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC50 of 400.2 ng/mL.
15.7 kDa, under reducing conditions; 15.7 kDa, under non-reducing conditions.
Molecule Type
Protein
Storage and Shipping
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Images
Recombinant Human IL-18 Protein (rp186564) - Binding Activity Immobilized Recombinant Human IL-18 Bpa Protein (rp169678) at 2.0 μg/mL can bind Recombinant Human IL-18 Protein (rp186564) with the EC
₅₀
of 30.0 ng/mL.
Recombinant Human IL-18 Protein (rp186564) - Binding Activity Immobilized Recombinant IL-18 protein (rp186564) at 1.0 μg/mL can bind Camoteskimab (anti-IL-18) (Ab182692) with the EC
₅₀
of 400.2 ng/mL.
Recombinant Human IL-18 Protein (rp186564) - SDS-PAGE 3 μg/lane of Recombinant Human IL-18 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 15.7 kDa.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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