Rifamycin B - ≥95% , CAS No.13929-35-6

CAS: 13929-35-6 Cat. No.: R335088 Molecular Weight: 755.8 Beilstein Registry Number: 604953 EC Number: 237-697-8 PubChem CID: 5459948

GRADE & PURITY ≥95%

Synonyms

Nancimycin | DTXSID901037384 | SCHEMBL637162 | Acetic acid, ((1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-9-yl)-oxy)-, 21-acetate | CHEBI:89827 | RIF

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Application

Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin derivative as antibacterial agent.

Specifications

Synonyms

Nancimycin | DTXSID901037384 | SCHEMBL637162 | Acetic acid, ((1, 2-dihydro-5, 6, 17, 19, 21-pentahydroxy-23-methoxy-2, 4, 12, 16, 18, 20, 22-heptamethyl-1, 11-dioxo-2, 7-(epoxypentadeca(1, 11, 13)trienimino)naphtho(2, 1-b)furan-9-yl)-oxy)-, 21-acetate | CHEBI:89827 | RIF

Specifications & Purity

≥95%

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504763825
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504763825
• Canonical Smiles: CC1C=CC=C(C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O)C
• IUPAC Name: 2-[[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-13-acetyloxy-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-27-yl]oxy]acetic acid
• InChIKey: SQTCRTQCPJICLD-KTQDUKAHSA-N
• INCHI: 1S/C39H49NO14/c1-17-11-10-12-18(2)38(49)40-24-15-26(51-16-27(42)43)28-29(34(24)47)33(46)22(6)36-30(28)37(48)39(8,54-36)52-14-13-25(50-9)19(3)35(53-23(7)41)21(5)32(45)20(4)31(17)44/h10-15,17,19-21,25,31-32,35,44-47H,16H2,1-9H3,(H,40,49)(H,42,43)/b11-10+,14-13+,18-12-/t17-,19+,20+,21+,25-,31-,32+,35+,39-/m0/s1
• Isomeric SMILES: C[C@H]1/C=C/C=C(\C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O)/C
• RTECS: AH0525000
• PubChem CID: 5459948
• Molecular Weight: 755.8
• Beilstein: 604953

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Class Macrolactams

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Class: Macrolactams
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Macrolactams
• Alternative Parents: Naphthofurans Phenoxyacetic acid derivatives Naphthols and derivatives Benzofurans Coumarans Aryl alkyl ketones Alkyl aryl ethers Ketals Dicarboxylic acids and derivatives Secondary carboxylic acid amides Secondary alcohols Carboxylic acid esters Lactams Polyols Oxacyclic compounds Azacyclic compounds Carboxylic acids Dialkyl ethers Organopnictogen compounds Organic oxides Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Naphthofuran - Macrolactam - 1-naphthol - Phenoxyacetate - Naphthalene - Benzofuran - Coumaran - Aryl alkyl ketone - Aryl ketone - Ketal - Alkyl aryl ether - Benzenoid - Dicarboxylic acid or derivatives - Ketone - Lactam - Carboxylic acid ester - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - Acetal - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Ether - Oxacycle - Azacycle - Organoheterocyclic compound - Polyol - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organopnictogen compound - Alcohol - Organic oxide - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as macrolactams. These are cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. They are nitrogen analogues (the a nitrogen atom replacing the o atom of the cyclic carboxylic acid group ) of the naturally occurring macrolides.
• External Descriptors: Ansamycins and related polyketides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in DMSO, ethyl acetate, and methanol.
• Sensitivity: Light sensitive
• Refractive Index: n20D1.63 (Predicted)
• Boil Point(°C): ~961.5° C at 760 mmHg (Predicted)
• Melt Point(°C): >168° C (dec.)
• Molecular Weight: 755.800 g/mol
• XLogP3: 4.800
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 6
• Exact Mass: 755.315 Da
• Monoisotopic Mass: 755.315 Da
• Topological Polar Surface Area: 228.000 Ų
• Heavy Atom Count: 54
• Formal Charge: 0
• Complexity: 1460.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 3
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 3
• Covalently-Bonded Unit Count: 1

References

1. Hong Khanh Trung, Dang Huu Phuc, Le Hanh Ngoc Thi, Dieu Nguyen, Duyen Ky, Nguyen Quoc Thang, Nguyen Van Cuong.  (2026)  Microwave-assisted synthesis of nitrogen-doped carbon quantum dots for dual fluorescence detection of Fe³⁺ ions and oxytetracycline.  APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING,  132  (3): (226).  [PMID:] [10.1007/s00339-026-09425-1]