RIP2 kinase inhibitor 2 - 10mM in DMSO , CAS No.1581270-11-2

CAS: 1581270-11-2 Cat. No.: R656883 Molecular Weight: 432.54 PubChem CID: 73426595

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

RIP2 kinase inhibitor 2 is a receptor interacting protein-2 ( RIP2 ) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9.

In Vitro

RIP2 kinase inhibitor 2 is a novel prodrug of a quinazolyl amine that inhibits RIP2 kinase. Receptor interacting protein-2 (RIP2) kinase is a TKL family serine/threonine protein kinase involved in innate immune signaling. Following activation, RIP2 kinase associates with NODI or NOD2 and appears to function principally as a molecular scaffold to bring together other kinases (TAK1, ΙΚΚα/β/γ) involved in NF-κΒ and mitogen-activated protein kinase activation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:RIP2 Kinase

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

RIP2 kinase inhibitor 2 is a receptor interacting protein-2 ( RIP2 ) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CC1=C(NN=C1NC2=C3C=C(C(=CC3=NC=C2)OCCOC)S(=O)(=O)C(C)(C)C)C
• PubChem CID: 73426595
• Molecular Weight: 432.54

Associated Targets(Human)

RIPK2 Tchem Receptor-interacting serine/threonine-protein kinase 2 (2 Activities)

Discover Target: RIPK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)