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· · COA & SDS available for every product · Same-day shipping on in-stock items Ro 04-6790 - Moligand™, ≥98%(HPLC) , Antagonist of 5-HT 6 receptor, CAS No.202466-68-0, Antagonist of 5-HT 6 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
Kiton Black HA | Q855636 | L000511 | 4-Amino-N-(2,6-bis-dimethylamino-pyrimidin-4-yl)-benzenesulfonamide | CU78RAR5ZH | DTXSID50187476 | Ro 04-6790 dihydrochloride | (4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide) | 4-Azanyl-N-(2,6-bis
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
Kiton Black HA | Q855636 | L000511 | 4-Amino-N-(2, 6-bis-dimethylamino-pyrimidin-4-yl)-benzenesulfonamide | CU78RAR5ZH | DTXSID50187476 | Ro 04-6790 dihydrochloride | (4-amino-N-[2, 6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide) | 4-Azanyl-N-(2, 6-bis
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective 5-HT6receptor antagonist (pKivalues are 7.26 and 7.35 at rat and human 5-HT6receptors respectively). Displays no affinity at a range of other receptors (IC50> 10μM). Induces stretching behavior in ratsin vivo.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Antagonist of 5-HT 6 receptor
Names and Identifiers Canonical Smiles CNC1=CC(=NC(=N1)NC)NS(=O)(=O)C2=CC=C(C=C2)N IUPAC Name 4-amino-N-[2,6-bis(methylamino)pyrimidin-4-yl]benzenesulfonamide InChIKey JELFWSXQTXRMAJ-UHFFFAOYSA-N INCHI 1S/C12H16N6O2S/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18) Isomeric SMILES CNC1=CC(=NC(=N1)NC)NS(=O)(=O)C2=CC=C(C=C2)N WGK Germany 3 RTECS DA9462500 Alternate CAS 202466-68-0 PubChem CID 5312145 MeSH Entry Terms 4-amino-N-(2,6 bis-methylamino-pyrimidin-4-yl)-benzene sulfonamide;Ro 04-6790;Ro 4-6790;Ro4-6790 Molecular Weight 308.36
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Benzenesulfonamides Intermediate Tree Nodes Not available Direct Parent Aminobenzenesulfonamides Alternative Parents Benzenesulfonyl compounds Aniline and substituted anilines Secondary alkylarylamines Aminopyrimidines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Aminobenzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Aminopyrimidine - Secondary aliphatic/aromatic amine - Pyrimidine - Organosulfonic acid amide - Imidolactam - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Heteroaromatic compound - Secondary amine - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic nitrogen compound - Amine - Organic oxide - Organopnictogen compound - Primary amine - Organosulfur compound - Organic oxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 30.84, Max Conc. mM: 100 Molecular Weight 308.360 g/mol XLogP3 1.700 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 5 Exact Mass 308.106 Da Monoisotopic Mass 308.106 Da Topological Polar Surface Area 130.000 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 418.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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