Rose bengal - ≥90% , CAS No.632-69-9

CAS: 632-69-9 Cat. No.: R104992 Summenformel: C₂₀H₂Cl₄I₄Na₂O₅ Molekulargewicht: 1017.64 Beilstein Registry Number: 3645857 EG-Nummer: 211-183-3 PubChem CID: 69438

GRADE & PURITY ≥90%

Synonyms

FT-0621857 | 2,4,5,7-Tetraido(m,p,o',m')tetrachlorofluorescein, disodium salt | Acid Red 94 disodium salt | MFCD00151169 | Rose bengale (131 I) sodique [INN-French] | F20361 | R105 sodium | disodium;4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-b

Storage

Protected from light,Room temperature,Desiccated

Shipped In

Normal

Übersicht

Product Description：
Rose Bengal is a stain used in the eye drops to identify the eye damage. It finds application in the preparation of foraminifera for microscopic analysis, photosensitizing reactions and as a dye. In synthetic chemistry, it is utilized to convert triplet oxygen to singlet oxygen, which is used in [2+2] cycloadditions with alkenes. Its derivatives have important medical functions and used for the treatment of cancer. It acts as an alternative to phloxine B in Kreyberg's stain for keratin and mucus. As a fluorescent probe, it is used for the determination of NAD binding sites of alcohol dehydrogenase. Product Application：
Rose Bengal is a red or rose color dye and is anionic in nature. It is a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodo derivative of fluorescein. It is widely used to detect damage to the ocular surface epithelium in ocular surface diseases such as dry eye and herpetic keratitis. Rose Bengal has mild antiviral potency.Rose Bengal is used to stain dead and degenerating cells and mucus.

Specifications

Synonyme

FT-0621857 | 2,4,5,7-Tetraido(m,p,o',m')tetrachlorofluorescein, disodium salt | Acid Red 94 disodium salt | MFCD00151169 | Rose bengale (131 I) sodique [INN-French] | F20361 | R105 sodium | disodium;4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-b

Spezifikationen & Reinheit

≥90%

Biochemische und physiologische Mechanismen

Potent glutamate uptake inhibitor (K i = 19 nM, glutamate uptake into isolated synaptic vesicles). Photosensitizing dye. Fluorescein derivative. Cell-permeable. Induces photothrombotic stroke in vivo.

Storage

Protected from light,Room temperature,Desiccated

Verschickt in

Normal

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥90%

Namen und Kennungen

Pubchem Sid

508813231

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508813231

Kanonisches Lächeln

C1=C2C(=C(C(=C1I)[O-])I)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)I)[O-])I.[Na+].[Na+]

IUPAC Name

disodium;4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate

InChIKey

KCQREHTWEUECQT-UHFFFAOYSA-L

INCHI

1S/C20H4Cl4I4O5.2Na/c21-9-7-8(10(22)12(24)11(9)23)20(33-19(7)31)3-1-5(25)15(29)13(27)17(3)32-18-4(20)2-6(26)16(30)14(18)28;;/h1-2,29-30H;;/q;2*+1/p-2

Isomere SMILES

C1=C2C(=C(C(=C1I)[O-])I)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)I)[O-])I.[Na+].[Na+]

WGK Deutschland

3

RTECS

LM5920000

PubChem CID

69438

Molekulargewicht

1017.64

Beilstein

3645857

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Benzopyrans
      • Subclass 1-benzopyrans
        • Ebene5 Dibenzopyrans
          • Ebene6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Diarylethers Phthalides Benzofuranones Isobenzofurans Phenoxides Aryl chlorides Aryl iodides Vinylogous halides Carboxylic acid esters Lactones Oxacyclic compounds Organic metal halides Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic sodium salts Organic zwitterions Organic oxides Organoiodides Organochlorides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Diaryl ether - Isobenzofuranone - Benzofuranone - Phthalide - Isocoumaran - Isobenzofuran - Phenoxide - Aryl chloride - Aryl halide - Aryl iodide - Benzenoid - Vinylogous halide - Carboxylic acid ester - Lactone - Organic metal halide - Carboxylic acid derivative - Oxacycle - Organic alkali metal salt - Ether - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organohalogen compound - Organochloride - Organoiodide - Organooxygen compound - Organic salt - Organic zwitterion - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Light sensitive.
• Schmelzpunkt (°C): >300℃
• Molekulargewicht: 1017.600 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 1017.46 Da
• Monoisotopic Mass: 1015.46 Da
• Topological Polar Surface Area: 81.700 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 780.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3