≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
SEL201 SEL-201 (SLV-2436, SEL201-88) is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively.
Targets
MNK2 (Cell-free assay); MNK1 (Cell-free assay) 5.4 nM; 10.8 nM
| ALogP | 3.044 |
|---|---|
| HBD Count | 2 |
| Rotatable Bond | 3 |
| Pubchem Sid | 504773043 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504773043 |
| Canonical Smiles | C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N |
| IUPAC Name | 5-(3-amino-1H-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one |
| InChIKey | YQVUADHJKWJHAF-UHFFFAOYSA-N |
| INCHI | 1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23) |
| Isomeric SMILES | C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N |
| PubChem CID | 129052025 |
| Molecular Weight | 350.8 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Benzopyrazoles |
| Subclass | Indazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indazoles |
| Alternative Parents | Chlorobenzenes Pyridines and derivatives Imidolactams Pyrazoles Heteroaromatic compounds Lactams Azacyclic compounds Primary amines Organopnictogen compounds Organooxygen compounds Organochlorides Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Indazole - Benzopyrazole - Halobenzene - Chlorobenzene - Imidolactam - Benzenoid - Pyridine - Monocyclic benzene moiety - Heteroaromatic compound - Pyrazole - Azole - Lactam - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as indazoles. These are compounds containing an indazole, which is structurally characterized by a pyrazole fused to a benzene. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2317498 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317513 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317514 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317515 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317535 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317544 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317549 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317555 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317559 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| F2317572 | Certificate of Analysis | Apr 02, 2026 | S413668 |
| Solubility | Solubility (25°C) In vitro DMSO: 70 mg/mL (199.54 mM); Ethanol: 5 mg/mL (14.25 mM); Water: Insoluble; |
|---|---|
| DMSO(mg / mL) Max Solubility | 70 |
| DMSO(mM) Max Solubility | 199.543899657925 |
| Water(mg / mL) Max Solubility | ＜1 |
| Molecular Weight | 350.800 g/mol |
| XLogP3 | 3.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 350.093 Da |
| Monoisotopic Mass | 350.093 Da |
| Topological Polar Surface Area | 75.000 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 578.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
