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SPOP-IN-6b dihydrochloride - ≥99% , CAS No.S658950
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM.
Appearance:Solid
In Vitro:SPOP-IN-6b dihydrochloride shows IC 50 s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN
In Vivo:SPOP-IN-6b (40-80mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Biological Activity:SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM.
Specifications
Specifications & Purity
≥99%
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
| Canonical Smiles | O=C(C(C(N1CCC2=CC=CC=C2)=N)=CC3=C1N=C(C(C)=CC=C4)N4C3=O)NCCCN5CCOCC5.[H]Cl.[H]Cl |
|---|---|
| Molecular Weight | 573.51 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 41.67 mg/mL (72.66 mM; ultrasonic and warming and heat to 60°C) |
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Solution Calculators
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Customer Reviews
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