SSB Mouse mAb - Primärer Antikörper, specific to SSB, Mouse IgG1

Cat. No.: Ab129231

GRADE & PURITY Validated, ExactAb™, 1.0 mg/mL

Application

WB

Host species

Maus

Reactive species

Mensch

Isotype

Mouse IgG1

Clone Number

4B10-E11-H11

Conjugation

Unconjugated

Übersicht

Mouse anti Human SSB Antibody, Monoclonal antibody (4B10-E11-H11), could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
Post-translational
Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein. The N-terminus is blocked.

Specifications

Product Name

SSB Mouse mAb - Primärer Antikörper, specific to SSB, Mouse IgG1

Synonyme

La antibody | La autoantigen antibody | La autoantigen homolog antibody | La protein antibody | La ribonucleoprotein antibody | La ribonucleoprotein domain family member 3 antibody | LA_HUMAN antibody | LARP3 antibody | Lupus La antigen antibody | Lupus L

Spezifikationen & Reinheit

ExactAb™, Validated, 1.0 mg/mL

Wirtsspezies

Maus

Spezifität

SSB

Immunogen

Recombinant protein of human SSB (AA 2-408)

Positive Kontrolle

WB: MCF7, A549, Jurkat, HeLa and Hep G2 cell lysates.

Konjugation

Unconjugated

Note

ExactAb™, Validated

Isotyp

Mouse IgG1

Lichterketten-Typ

kappa

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Protein G purified

Konzentration

1.0 mg/mL

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Western Blot: SSB Mouse mAb (Ab129231)

SSB Mouse mAb (Ab129231) - Western Blot
All lanes: SSB Mouse mAb (Ab129231) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution

Predicted band size: 47 kDa
Observed band size: 48 kDa
Exposure time: 9.8 s

Anwendung

• Anwendung: Dilution info
• WB:

  1/500-1/1000

Zugehörige Ziele (menschlich)

SSB Tbio Lupus La protein (0 Activities)

Discover Target: SSB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Wirkungsmechanismen

Häufig gestellte Fragen

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Validated mean?

Validated indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (SSB Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.