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· · COA & SDS available for every product · Same-day shipping on in-stock items Suvecaltamide - ≥99% , Voltage-gated T-type calcium channel modulator, CAS No.953778-58-0, Voltage-gated T-type calcium channel modulator
Synonyms
compound 1 [PMID: 27579577] | UNII-MIA4WMP8QN | SUVECALTAMIDE [INN] | 2-PYRAZINECARBOXAMIDE, 3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-(DIMETHYLAMINO)- | Cx-8998 | 2-(4-propan-2-ylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide | 4-
Shipped In
Ice chest + Ice pads
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Why this grade ≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Suvecaltamide (MK-8998; compound 33) is a potent and selective inhibitor of the T-type calcium channel .
Form:Solid
IC50& Target:T-type calcium channel
Specifications Synonyms
compound 1 [PMID: 27579577] | UNII-MIA4WMP8QN | SUVECALTAMIDE [INN] | 2-PYRAZINECARBOXAMIDE, 3-AMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-5-(DIMETHYLAMINO)- | Cx-8998 | 2-(4-propan-2-ylphenyl)-N-[(1R)-1-[5-(2, 2, 2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide | 4-
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
Suvecaltamide (MK-8998; compound 33) is a potent and selective inhibitor of the T-type calcium channel .
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Voltage-gated T-type calcium channel modulator
Product Properties Names and Identifiers Canonical Smiles CC(C)C1=CC=C(C=C1)CC(=O)NC(C)C2=NC=C(C=C2)OCC(F)(F)F IUPAC Name 2-(4-propan-2-ylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide InChIKey IQIKXZMPPBEWAD-CQSZACIVSA-N INCHI 1S/C20H23F3N2O2/c1-13(2)16-6-4-15(5-7-16)10-19(26)25-14(3)18-9-8-17(11-24-18)27-12-20(21,22)23/h4-9,11,13-14H,10,12H2,1-3H3,(H,25,26)/t14-/m1/s1 Isomeric SMILES C[C@H](C1=NC=C(C=C1)OCC(F)(F)F)NC(=O)CC2=CC=C(C=C2)C(C)C Alternate CAS 953778-58-0 PubChem CID 24765479 Molecular Weight 380.4
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Lipids and lipid-like molecules Class Prenol lipids Subclass Monoterpenoids Intermediate Tree Nodes Not available Direct Parent Aromatic monoterpenoids Alternative Parents Phenylacetamides Monocyclic monoterpenoids Phenylpropanes Cumenes Alkyl aryl ethers Pyridines and derivatives Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents P-cymene - Aromatic monoterpenoid - Monocyclic monoterpenoid - Phenylacetamide - Cumene - Phenylpropane - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Pyridine - Heteroaromatic compound - Carboxamide group - Secondary carboxylic acid amide - Organoheterocyclic compound - Carboxylic acid derivative - Azacycle - Ether - Organic nitrogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alkyl halide - Alkyl fluoride - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as aromatic monoterpenoids. These are monoterpenoids containing at least one aromatic ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO : 100 mg/mL (262.88 mM; Need ultrasonic) Molecular Weight 380.400 g/mol XLogP3 4.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 7 Exact Mass 380.171 Da Monoisotopic Mass 380.171 Da Topological Polar Surface Area 51.200 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 463.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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