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· · COA & SDS available for every product · Same-day shipping on in-stock items TC-A 2317 hydrochloride - ≥98%(HPLC) , CAS No.1245907-03-2
Synonyms
TC-A 2317 (hydrochloride) | J-005099 | 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrilehydrochloride | VZB90703 | HY-103266 | TC-A2317 hydrochloride | 2-[(6-hydroxy-6-methylheptan-2-yl)amino]-4-met
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
TC-A 2317 (hydrochloride) | J-005099 | 2-[(5-Hydroxy-1, 5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrilehydrochloride | VZB90703 | HY-103266 | TC-A2317 hydrochloride | 2-[(6-hydroxy-6-methylheptan-2-yl)amino]-4-met
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent Aurora kinase A inhibitor (Ki= 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50values > 1000 nM). Exhibits good cell permeability and antitumor activity.
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles CC1=CC(=NC(=C1C#N)NC(C)CCCC(C)(C)O)NC2=NNC(=C2)C.Cl IUPAC Name 2-[(6-hydroxy-6-methylheptan-2-yl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile;hydrochloride InChIKey DXVATYHPJJPMIN-UHFFFAOYSA-N INCHI 1S/C19H28N6O.ClH/c1-12-9-16(22-17-10-14(3)24-25-17)23-18(15(12)11-20)21-13(2)7-6-8-19(4,5)26;/h9-10,13,26H,6-8H2,1-5H3,(H3,21,22,23,24,25);1H Isomeric SMILES CC1=CC(=NC(=C1C#N)NC(C)CCCC(C)(C)O)NC2=NNC(=C2)C.Cl PubChem CID 46911725 Molecular Weight 392.93
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyridines and derivatives Subclass 3-pyridinecarbonitriles Intermediate Tree Nodes Not available Direct Parent 3-pyridinecarbonitriles Alternative Parents Secondary alkylarylamines Methylpyridines Aminopyridines and derivatives Imidolactams Tertiary alcohols Pyrazoles Heteroaromatic compounds Nitriles Azacyclic compounds Hydrochlorides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents 3-pyridinecarbonitrile - Aminopyridine - Methylpyridine - Secondary aliphatic/aromatic amine - Imidolactam - Azole - Pyrazole - Heteroaromatic compound - Tertiary alcohol - Carbonitrile - Nitrile - Secondary amine - Azacycle - Cyanide - Organooxygen compound - Organonitrogen compound - Amine - Alcohol - Organic oxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Hydrochloride - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as 3-pyridinecarbonitriles. These are organic compounds containing a pyridine ring substituted at the 3-position by a carbonitrile group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 39.29, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 19.65, Max Conc. mM: 50 Molecular Weight 392.900 g/mol XLogP3 Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 8 Exact Mass 392.209 Da Monoisotopic Mass 392.209 Da Topological Polar Surface Area 110.000 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 490.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
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