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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Tyrphostin RG 14620 is a non-phenolic tyrphostin analog, which is selective for the EGFR (EGF receptor). The compound inhibits EGF-stimulated HER14 cell proliferation (IC|50|=3 μM) as well as tumor growth in vivo. Tyrphostin RG 14620 contains anti-proliferative effects on renal and bladder carcinoma cell lines. Tyrphostin RG 14620 is an inhibitor of Tyrosine Kinase.
| Pubchem Sid | 504763664 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504763664 |
| Canonical Smiles | C1=CC(=CN=C1)C(=CC2=CC(=CC(=C2)Cl)Cl)C#N |
| IUPAC Name | (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile |
| InChIKey | TYXIVBJQPBWBHO-QCDXTXTGSA-N |
| INCHI | 1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4- |
| Isomeric SMILES | C1=CC(=CN=C1)/C(=C\C2=CC(=CC(=C2)Cl)Cl)/C#N |
| WGK Germany | 3 |
| PubChem CID | 5353928 |
| Molecular Weight | 275.1 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Halobenzenes |
| Intermediate Tree Nodes | Chlorobenzenes |
| Direct Parent | Dichlorobenzenes |
| Alternative Parents | Pyridines and derivatives Aryl chlorides Heteroaromatic compounds Nitriles Azacyclic compounds Organochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | 1,3-dichlorobenzene - Aryl chloride - Aryl halide - Pyridine - Heteroaromatic compound - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organohalogen compound - Organic nitrogen compound - Organochloride - Organonitrogen compound - Cyanide - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 11, 2026 | T337827 | |
| Certificate of Analysis | Feb 07, 2025 | T337827 | |
| Certificate of Analysis | Feb 07, 2025 | T337827 | |
| Certificate of Analysis | Feb 07, 2025 | T337827 | |
| Certificate of Analysis | Feb 07, 2025 | T337827 |
| Solubility | Soluble in DMSO (25 mg/mL), and acetone (25 mg/mL). Insoluble in water. |
|---|---|
| Sensitivity | Heat sensitive |
| Refractive Index | n20D1.66 |
| Boil Point(°C) | 418.23° C at 760 mmHg |
| Melt Point(°C) | 150-151° C |
| Molecular Weight | 275.100 g/mol |
| XLogP3 | 3.900 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 274.006 Da |
| Monoisotopic Mass | 274.006 Da |
| Topological Polar Surface Area | 36.700 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 348.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |