Vincristine sulfate - PharmPure™, USP , CAS No.2068-78-2

CAS: 2068-78-2 Cat. No.: V432299 Molecular Weight: 923.04 Beilstein Registry Number: 3924631 EC Number: 218-190-0 PubChem CID: 249332

11 Citations COA

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Vincristine sulfate - PharmPure™, USP CAS No(2068-78-2) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY PharmPure™ ? USP ?

Synonyms

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product References Solution Calculators Reviews

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Why this grade

PharmPure™, USP PharmPure™,USP for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

General Description

Vincristine sulfate is an alkaloid present in Cantharanthus roseus .

Application

Vincristine sulfate has been used: as a positive control in potato disc anti-tumor bioassay as a standard cytotoxic agent to treat cells for manipulation of the microtubule network

Specifications

Synonyms

Specifications & Purity

PharmPure™, USP

Biochemical and Physiological Mechanisms

Vincristine sulfate possesses antitumor action targeting cell cycle. It prevents the action of tubulin by inhibiting microtubule polymerization. It also causes cell death and blocks metaphase in mitosis by preventing chromosome segregation. Vincristine su

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

PharmPure™, USP

Names and Identifiers

Canonical Smiles	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
IUPAC Name	methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid
InChIKey	AQTQHPDCURKLKT-JKDPCDLQSA-N
INCHI	1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+;/m1./s1
Isomeric SMILES	CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Alternate CAS	57-22-7(free base)
PubChem CID	249332
UN Number	1544
Packing Group	I
Molecular Weight	923.04
Beilstein	3924631

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Class Vinca alkaloids

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Class	Vinca alkaloids
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Vinca alkaloids
Alternative Parents	Carbazoles 3-alkylindoles Tricarboxylic acids and derivatives Anisoles Aralkylamines Alkyl aryl ethers N-alkylpyrrolidines Piperidines Organic sulfuric acids Methyl esters Pyrroles Heteroaromatic compounds Tertiary alcohols Tertiary carboxylic acid amides Trialkylamines Cyclic alcohols and derivatives Amino acids and derivatives 1,2-aminoalcohols Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Vinca alkaloid skeleton - Carbazole - 3-alkylindole - Indole - Indole or derivatives - Tricarboxylic acid or derivatives - Anisole - Alkyl aryl ether - Sulfuric acid - Aralkylamine - Piperidine - Benzenoid - N-alkylpyrrolidine - Cyclic alcohol - Heteroaromatic compound - Organic sulfuric acid or derivatives - Pyrrole - Pyrrolidine - Tertiary alcohol - Tertiary carboxylic acid amide - Methyl ester - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Carboxamide group - 1,2-aminoalcohol - Carboxylic acid ester - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Ether - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Carbonyl group - Amine - Alcohol - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as vinca alkaloids. These are alkaloids with a dimeric chemical structure composed of an indole nucleus (catharanthine), and a dihydroindole nucleus (vindoline), joined together.
External Descriptors	organic molecular entity
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A 172 (535 Activities)

Melt Point(°C)	300 °C
Molecular Weight	923.000 g/mol
XLogP3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	10
Exact Mass	922.367 Da
Monoisotopic Mass	922.367 Da
Topological Polar Surface Area	254.000 Å²
Heavy Atom Count	65
Formal Charge	0
Complexity	1830.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Vincristine sulfate - PharmPure™, USP , CAS No.2068-78-2

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

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Reconstitution Calculator

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