≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells.
| Pubchem Sid | 488201163 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201163 |
| Canonical Smiles | C1=CC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OC(F)(F)F)C(=O)C3=O |
| IUPAC Name | 1-[(4-phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione |
| InChIKey | SPBGRXOPAXZSER-UHFFFAOYSA-N |
| INCHI | 1S/C22H14F3NO3/c23-22(24,25)29-17-10-11-19-18(12-17)20(27)21(28)26(19)13-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-12H,13H2 |
| Isomeric SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OC(F)(F)F)C(=O)C3=O |
| PubChem CID | 45281794 |
| Molecular Weight | 397.35 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Biphenyls and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Biphenyls and derivatives |
| Alternative Parents | Indoles and derivatives Aryl ketones Vinylogous amides Tertiary carboxylic acid amides Trihalomethanes Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Biphenyl - Indole or derivatives - Aryl ketone - Vinylogous amide - Tertiary carboxylic acid amide - Carboxamide group - Trihalomethane - Ketone - Lactam - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Alkyl fluoride - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Halomethane - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Alkyl halide - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C23311495 | Certificate of Analysis | Jan 29, 2026 | V287332 |
| C23311482 | Certificate of Analysis | Jan 29, 2026 | V287332 |
| C23311481 | Certificate of Analysis | Jan 29, 2026 | V287332 |
| C23311477 | Certificate of Analysis | Jan 29, 2026 | V287332 |
| C23311475 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311476 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311478 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311479 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311480 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311484 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311485 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| C23311489 | Certificate of Analysis | Jan 20, 2026 | V287332 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 39.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.97, Max Conc. mM: 10 |
|---|---|
| Molecular Weight | 397.300 g/mol |
| XLogP3 | 5.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 397.093 Da |
| Monoisotopic Mass | 397.093 Da |
| Topological Polar Surface Area | 46.600 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 609.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
