Determine the necessary mass, volume, or concentration for preparing a solution.
XPC-6444 - 10mM in DMSO , CAS No.2230144-21-3
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
XPC-6444 is a highly potent, isoform-selective, and CNS-penetrant Na V 1.6 inhibitor ( IC 50 =41 nM for hNa V 1.6). XPC-6444 also displays potent block of Na V 1.2 (IC 50 =125 nM). XPC-6444 shows anticonvulsant activity
In Vitro
XPC-6444 shows high selectivity over Na V 1.1 and Na V 1.5. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
XPC-6444 exhibits good metabolic stability in human liver microsomes and hepatocytes, and low potential for MDR1 mediated efflux . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 41 nM (hNa V 1.6), 125 nM (hNa V 1.2)
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
XPC-6444 is a highly potent, isoform-selective, and CNS-penetrant Na V 1.6 inhibitor ( IC 50 =41 nM for hNa V 1.6). XPC-6444 also displays potent block of Na V 1.2 (IC 50 =125 nM). XPC-6444 shows anticonvulsant activity.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
| Molecular Weight | 498.58 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews
Customer Reviews
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.