YAP-TEAD-IN-1 TFA - ≥99% , CAS No.1659305-79-9

CAS: 1659305-79-9 Cat. No.: Y649947 Molecular Weight: 2133.88

GRADE & PURITY ≥99%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction ( IC 50 =25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 ( K d =15 nM) than YAP (50-171) ( K d = 40 nM)

In Vitro

YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K d of His-YAP(1209-426) is determined to be 40 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 25 nM (YAP-TEAD interaction)

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction ( IC 50 =25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 ( K d =15 nM) than YAP (50-171) ( K d = 40 nM).

Storage

Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Molecular Weight: 2133.88

Chemical and Physical Properties

• Solubility: H2O : ≥ 50 mg/mL (23.43 mM)