≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator ( uPA ) inhibitor as a potential treatment for multiple sclerosis. IC 50 s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.
In Vivo
ZK824190 (2 mg/kg; PO; Rats with EAE model) exhibits a relatively high oral availability and a moderate half time (T 1/2 =2.8 h) . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator ( uPA ) inhibitor as a potential treatment for multiple sclerosis. IC 50 s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.
Storage
Protected from light, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
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