1,3-Di-4-piperidylpropane - ≥97%(GC) , CAS No.16898-52-5

CAS: 16898-52-5 Cat. No.: D154524 Molecular Weight: 210.37 EC Number: 240-941-6

GRADE & PURITY ≥97%(GC)

Synonyms

4,4'-Trimethylenedipiperidine, 97% | OXEZLYIDQPBCBB-UHFFFAOYSA- | D97682 | REC 7/0267 | D0293 | CAS-31112-62-6 | Maybridge4_003634 | 4,4'-(1,3-Propanediyl)bis[piperidine] | Q27277371 | 4,3-Propanediyl)bispiperidine | STR05333 | 1,3-bis(4-piperidinyl)propa

Storage

Room temperature,Argon charged,Desiccated,Cool

Shipped In

Normal

Overview

4,4′-Trimethylenedipyridine undergoes Willgerodt-Kindler reaction by on pot- polycondensation with dialdehydes in the presence of sulphur to form polythioamides.

Specifications

Synonyms

4, 4'-Trimethylenedipiperidine, 97% | OXEZLYIDQPBCBB-UHFFFAOYSA- | D97682 | REC 7/0267 | D0293 | CAS-31112-62-6 | Maybridge4_003634 | 4, 4'-(1, 3-Propanediyl)bis[piperidine] | Q27277371 | 4, 3-Propanediyl)bispiperidine | STR05333 | 1, 3-bis(4-piperidinyl)propa

Specifications & Purity

≥97%(GC)

Storage

Room temperature, Argon charged, Desiccated, Cool

Shipped In

Normal

Purity

≥97%(GC)

Names and Identifiers

• Pubchem Sid: 488186338
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488186338
• Canonical Smiles: C1CNCCC1CCCC2CCNCC2
• IUPAC Name: 4-(3-piperidin-4-ylpropyl)piperidine
• InChIKey: OXEZLYIDQPBCBB-UHFFFAOYSA-N
• INCHI: 1S/C13H26N2/c1(2-12-4-8-14-9-5-12)3-13-6-10-15-11-7-13/h12-15H,1-11H2
• Isomeric SMILES: C1CNCCC1CCCC2CCNCC2
• WGK Germany: 3
• Molecular Weight: 210.37
• Reaxy-Rn: 2521
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2521&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Dialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Piperidine - Azacycle - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water
• Sensitivity: Hygroscopic
• Specific Rotation[α]: >110℃(230°F)
• Boil Point(°C): 327℃
• Melt Point(°C): 65-68℃
• Molecular Weight: 210.360 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 210.21 Da
• Monoisotopic Mass: 210.21 Da
• Topological Polar Surface Area: 24.100 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 140.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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2. Hongyan Zhang, Shuang Dong, Sheng Zhang, Yufen Li, Ji Li, Yinghui Dai, Dongkai Wang.  (2020)  pH-responsive lipid polymer hybrid nanoparticles (LPHNs) based on poly (β-amino ester) as a promising candidate to resist breast cancers.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2020.102102]

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5. Jing Guo, Rui Liu, Chunhui Shen, Shanjun Gao.  (2025)  Anion Exchange Membranes of Alkaline Resistance Based on Acrylonitrile-Styrene Copolymer with N-Spirocyclic Ammonium.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.4c06302]

6. Xing Liu, Ting Zhang, Lei Zhou, Ming Li, Rongxing He.  (2024)  Dual-Emissive γ-[Cu4I8]4– Enables Luminescent Thermochromism in an Organic–Inorganic Hybrid Copper(I) Halide.  INORGANIC CHEMISTRY,      [PMID:38511502] [10.1021/acs.inorgchem.3c04141]

7. Yanchao Zhang, Jingyi Wu, Song Wang, Junjian Yu, Yiman Gu, Yan Wang, Jian Gao, Chang Sun, Zhanyu Li, Yijia Lei, Na Li, Jialin Zhao, Zhe Wang.  (2024)  Poly(p-terphenyl-piperidine-bromoacetophenone) anion exchange membranes with pendant N-spirocyclic cations: Cations synergistic build efficient ion transport networks.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.123134]