1,8-Bis(dimethylamino)naphthalene [for Dehydrohalogenation] - ≥98%(GC) , CAS No.20734-58-1

CAS: 20734-58-1 Cat. No.: B132323 Molecular Weight: 214.31 Beilstein Registry Number: 396782 EC Number: 244-001-6

GRADE & PURITY ≥98%(GC)

Synonyms

DMAN | 1,8-bis(dimethylamino)naphthalin | N,N,N',N'-Tetramethyl-1,8-naphthalenediamine, purum, >=99.0% (NT) | 1,8-Bis(dimethylamino)naphtalene | 1,8-Bis(dimethylamino)-naphtalene | Maybridge1_002116 | N,N,N',N'-Tetramethyl-1,8-diaminonaphthalene | N-[8-(d

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

1,8-Bis(dimethylamino)naphthalene is a very strong base with weak nucleophilic character due to steric effects.
Proton-sponge can be used in the synthesis of C-substituted t-BuNH-8,9-R,R′-nido-7,8,9-C3B8H9 (R,R′ = H,H; MeH; Me,Me; Ph,H and Ph,Ph) tricarbollide compounds. It was also used in the preparation of saturated fluoroalkyl(hydrido) complexes of Iridium.

Specifications

Synonyms

DMAN | 1, 8-bis(dimethylamino)naphthalin | N, N, N', N'-Tetramethyl-1, 8-naphthalenediamine, purum, >=99.0% (NT) | 1, 8-Bis(dimethylamino)naphtalene | 1, 8-Bis(dimethylamino)-naphtalene | Maybridge1_002116 | N, N, N', N'-Tetramethyl-1, 8-diaminonaphthalene | N-[8-(d

Specifications & Purity

≥98%(GC)

Storage

Store at 2-8°C, Protected from light, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(GC)

Names and Identifiers

• Pubchem Sid: 504755954
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504755954
• Canonical Smiles: CN(C)C1=CC=CC2=C1C(=CC=C2)N(C)C
• IUPAC Name: 1-N,1-N,8-N,8-N-tetramethylnaphthalene-1,8-diamine
• InChIKey: GJFNRSDCSTVPCJ-UHFFFAOYSA-N
• INCHI: 1S/C14H18N2/c1-15(2)12-9-5-7-11-8-6-10-13(14(11)12)16(3)4/h5-10H,1-4H3
• Isomeric SMILES: CN(C)C1=CC=CC2=C1C(=CC=C2)N(C)C
• WGK Germany: 3
• Molecular Weight: 214.31
• Beilstein: 396782
• Reaxy-Rn: 396782
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=396782&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Naphthalenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Naphthalenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenes
• Alternative Parents: Dialkylarylamines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Naphthalene - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Tertiary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in methanol, and chloroform. Insoluble in water.Soluble in organic solvents
• Sensitivity: Air & Light sensitive
• Flash Point(°F): >230°F
• Flash Point(°C): >110°C
• Boil Point(°C): 145 °C/4 mmHg
• Melt Point(°C): 48 °C
• Molecular Weight: 214.310 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 214.147 Da
• Monoisotopic Mass: 214.147 Da
• Topological Polar Surface Area: 6.500 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 203.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xiao-Pan Liu, Wen-Qian Sun, Tong-Xin Liu, Bing-Bing Liu, Chang-Po Chen.  (2021)  Fullerenol as a water-soluble MALDI-MS matrix for rapid analysis of small molecules and efficient quantification of saccharin sodium in foods.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:34130205] [10.1016/j.jchromb.2021.122819]