2-Fluoro-5-(trifluoromethyl)phenol - ≥98% , CAS No.141483-15-0

CAS: 141483-15-0 Cat. No.: F122602 Molecular Weight: 180.1 Beilstein Registry Number: 8392138 EC Number: 626-640-6
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
4-Fluoro-3-hydroxybenzotrifluoride | F0780 | 2-Fluoro-5-(trifluoromethyl)phenol | BisphenolC | 2-fluoro-5-trifluoromethylphenol | 2-Fluoro-5-trifluoromethyl-phenol | 5-(trifluoromethyl)-2-fluorophenol | DS-0822 | AC-3811 | AM20060191 | AKOS005258020 | EN3
Storage
Protected from light,Argon charged,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1g
F122602-1g
2

$9.90

$14.90
Save $5.00 (33.56%)
5g
F122602-5g
10

$13.90

$20.90
Save $7.00 (33.49%)
25g
F122602-25g
5

$34.90

$52.90
Save $18.00 (34.03%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 16 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
4-Fluoro-3-hydroxybenzotrifluoride | F0780 | 2-Fluoro-5-(trifluoromethyl)phenol | BisphenolC | 2-fluoro-5-trifluoromethylphenol | 2-Fluoro-5-trifluoromethyl-phenol | 5-(trifluoromethyl)-2-fluorophenol | DS-0822 | AC-3811 | AM20060191 | AKOS005258020 | EN3
Specifications & Purity
≥98%
Storage
Protected from light, Argon charged, Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488189995
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189995
Canonical SmilesC1=CC(=C(C=C1C(F)(F)F)O)F
IUPAC Name2-fluoro-5-(trifluoromethyl)phenol
InChIKeyMCOSBFKOUQAIJS-UHFFFAOYSA-N
INCHI1S/C7H4F4O/c8-5-2-1-4(3-6(5)12)7(9,10)11/h1-3,12H
Isomeric SMILES C1=CC(=C(C=C1C(F)(F)F)O)F
WGK Germany 3
Molecular Weight 180.1
Beilstein 8392138
Reaxy-Rn 8392138
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8392138&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassTrifluoromethylbenzenes
Intermediate Tree Nodes Not available
Direct ParentTrifluoromethylbenzenes
Alternative Parents O-fluorophenols  Fluorobenzenes  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Aryl fluorides  Organooxygen compounds  Organofluorides  Hydrocarbon derivatives  Alkyl fluorides  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Trifluoromethylbenzene - 2-halophenol - 2-fluorophenol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Alkyl fluoride - Organohalogen compound - Organofluoride - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Alkyl halide - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as trifluoromethylbenzenes. These are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
G2314102Certificate of AnalysisFeb 07, 2023 F122602
I1423154Certificate of AnalysisFeb 07, 2023 F122602
B2322723Certificate of AnalysisOct 09, 2022 F122602
B2322762Certificate of AnalysisOct 09, 2022 F122602
Chemical and Physical Properties
SensitivityAir Sensitive
Refractive Index1.439
Flash Point(°F)134.6 °F
Flash Point(°C)57°C(Lit.)
Boil Point(°C)146°C
Molecular Weight180.100 g/mol
XLogP32.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass180.02 Da
Monoisotopic Mass180.02 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count12
Formal Charge0
Complexity156.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Jizhong Wu, Wenya Wei, Muhammad Zareef, Shuhua Li, Qin Ouyang, Quansheng Chen.  (2023)  Simple design of upconversion nanoparticles-based aptasensor integrated microfluidic chip for ultra-sensitive detection of bisphenol A in aquatic products.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2023.134017]
2. Haoyu Long, Yanhao Jiang, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang.  (2023)  Chromatographic separation performance of silica microspheres surface-modified with triazine-containing imine-linked covalent organic frameworks.  TALANTA,      [PMID:37126925] [10.1016/j.talanta.2023.124589]
3. Yukun Yang, Xiaoxing Zeng, Yu Tian, Xiaomin Wang, Xu Jing, Ligang Yu, Baoqing Bai, Jinhua Zhang, Shu Qin.  (2023)  A universal design of turn-on fluorescent aptasensor based on luminescent MOFs: Application for the detection of bisphenol A in water, milk and chicken samples.  FOOD CHEMISTRY,      [PMID:37137241] [10.1016/j.foodchem.2023.136167]
4. Zhefei Hu, Yanhao Jiang, Panpan Cao, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang.  (2023)  Performance evaluation of 2-undecylimidazole/propyl methacrylate bifunctional silica gel for mixed-mode reversed-phase/anion-exchange chromatography.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.108768]
5. Qingying Wang, Lianfang Chen, Xiaoyan Cui, Jie Zhang, Yaohui Wang, Xiupei Yang.  (2023)  Determination of trace bisphenols in milk based on Fe3O4@NH2-MIL-88(Fe)@TpPa magnetic solid-phase extraction coupled with HPLC.  TALANTA,      [PMID:36657241] [10.1016/j.talanta.2023.124268]
6. Yan Wu, Panpan Cao, Yanhao Jiang, Yanjuan Liu, Yuefei Zhang, Wei Chen, Zhengwu Bai, Sheng Tang.  (2022)  Ingenious introduction of aminopropylimidazole to tune the hydrophobic selectivity of dodecyl-bonded stationary phase for environmental organic pollutants.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.107933]
7. Chengjiang Zhang, Hongmei Yuan, Zeyi Lu, Yuhuang Li, Lirong Zhao, Zhuomin Zhang, Gongke Li.  (2022)  β-Ketoenamine-linked covalent organic framework absorbent for online micro-solid phase extraction of trace levels bisphenols in plastic samples.  JOURNAL OF SEPARATION SCIENCE,  45  (9): (1493-1501).  [PMID:35157355] [10.1002/jssc.202100905]
8. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang.  (2022)  Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:35085896] [10.1016/j.chroma.2022.462834]
9. Weiwei Ma, Shuangfeng Wan, Chenchen Lin, Xucong Lin, Zenghong Xie.  (2020)  Towards online specific recognition and sensitive analysis of bisphenol A by using AuNPs@aptamer hybrid-silica affinity monolithic column with LC-MS.  TALANTA,      [PMID:32887165] [10.1016/j.talanta.2020.121275]
10. Sun Qianqian, Gao Chaohong, Ma Wende, He Yanting, Wu Jie, Luo Kailong, Ouyang Dan, Lin Zian, Cai Zongwei.  (2020)  High-throughput screening of bisphenols using magnetic covalent organic frameworks as a SELDI-TOF-MS probe.  MICROCHIMICA ACTA,  187  (7): (1-11).  [PMID:32504203] [10.1007/s00604-020-04340-5]
11. Shuo Li, Huizhong Si, Jianshu Li, Mengtian Jia, Xiaohong Hou.  (2020)  Metal organic framework/chitosan foams functionalized with polyethylene oxide as a sorbent for enrichment and analysis of bisphenols in beverages and water.  NEW JOURNAL OF CHEMISTRY,  44  (4): (1485-1492).  [PMID:] [10.1039/C9NJ05196A]
12. Yukun Yang, Xiaoyi Zhang, Xiaomin Wang, Xu Jing, Ligang Yu, Baoqing Bai, Tao Bo, Jinhua Zhang, Hailong Qian, Ying Gu.  (2024)  Self-powered molecularly imprinted photoelectrochemical sensor based on Ppy/QD/HOF heterojunction for the detection of bisphenol A.  FOOD CHEMISTRY,      [PMID:38277929] [10.1016/j.foodchem.2024.138499]
13. Qidong Yu, Wenmin Zhang, Jingyi Wang, Shiye Xie, Baodi Liao, Hui Chen, Qingqing Ding, Lan Zhang.  (2024)  Thiocarbamide conversion-based nitrogen-rich covalent organic framework coatings for electro-enhanced solid-phase microextraction of bisphenols.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38763086] [10.1016/j.chroma.2024.465000]
14. Kaixing Luo, Yu Luo, Yanjuan Liu, Yuefei Zhang, Wei Chen, Zhengwu Bai, Sheng Tang.  (2022)  Hydrophobic and hydrophilic selectivity of a multifunctional carbonyldiimidazolium/dodecyl modified silica stationary phase.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:35810643] [10.1016/j.chroma.2022.463300]
15. Ruifang Qi, Yue Zhao, Jinming Lei, Huixian Jia, Chenghong Feng.  (2026)  Nitro-electron trapping engineering for enhanced BPA degradation by metal free nitro-COFs.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2026.136975]
16. Jinglin Chen, Xiaoying Feng, Tingting Tu, Chunying Wei, Yongsheng Cui, Juan Zheng, Gangfeng Ouyang.  (2026)  Modified biochar through synergistic strategies for enhanced extraction of bisphenol compounds in marine water.  ANALYTICA CHIMICA ACTA,      [PMID:] [10.1016/j.aca.2026.345372]
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