2-Phenoxyacetophenone - ≥98% , CAS No.721-04-0

CAS: 721-04-0 Cat. No.: P160295 Molecular Weight: 212.25 EC Number: 660-275-3 PubChem CID: 222171
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
2-phenoxyacetophenone | AS-57740 | 2-phenoxy-1-phenylethanone | 2-phenoxy-1-phenyl-ethanone | MLS002638022 | 2-phenoxy-1-phenylethan-1-one | A856467 | AKOS008908306 | KRSXGTAVHIDVPM-UHFFFAOYSA-N | SY056476 | CHEBI:52401 | a-phenoxyacetophenone | NSC7586 |
Storage
Room temperature,Desiccated,Cool
Shipped In
Normal
Size
USA
Germany (EU)*
Price
Qty
250mg
P160295-250mg
3 In stock
$9.90
1g
P160295-1g
2 In stock
$29.90
5g
P160295-5g
US Made to order · 2–4 wks ·
$99.90
25g
P160295-25g
1 In stock
$339.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated,Cool Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2-phenoxyacetophenone | AS-57740 | 2-phenoxy-1-phenylethanone | 2-phenoxy-1-phenyl-ethanone | MLS002638022 | 2-phenoxy-1-phenylethan-1-one | A856467 | AKOS008908306 | KRSXGTAVHIDVPM-UHFFFAOYSA-N | SY056476 | CHEBI:52401 | a-phenoxyacetophenone | NSC7586 |
Specifications & Purity
≥98%
Storage
Room temperature, Desiccated, Cool
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488188698
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488188698
Canonical SmilesC1=CC=C(C=C1)C(=O)COC2=CC=CC=C2
IUPAC Name2-phenoxy-1-phenylethanone
InChIKeyKRSXGTAVHIDVPM-UHFFFAOYSA-N
INCHI1S/C14H12O2/c15-14(12-7-3-1-4-8-12)11-16-13-9-5-2-6-10-13/h1-10H,11H2
Isomeric SMILES C1=CC=C(C=C1)C(=O)COC2=CC=CC=C2
PubChem CID 222171
Molecular Weight 212.25
Reaxy-Rn 1873445

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassCarbonyl compounds
Intermediate Tree Nodes Ketones - Aryl ketones - Phenylketones
Direct ParentAlkyl-phenylketones
Alternative Parents Phenoxy compounds  Phenol ethers  Benzoyl derivatives  Aryl alkyl ketones  Alkyl aryl ethers  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Alkyl-phenylketone - Phenoxy compound - Aryl alkyl ketone - Phenol ether - Benzoyl - Alkyl aryl ether - Benzenoid - Monocyclic benzene moiety - Ether - Organic oxide - Hydrocarbon derivative - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors 2-aryloxyketone
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

23 results found

Lot NumberCertificate TypeDateItem
F2612487Certificate of AnalysisJun 04, 2026 P160295
F2612489Certificate of AnalysisJun 04, 2026 P160295
F2612490Certificate of AnalysisJun 04, 2026 P160295
F2612491Certificate of AnalysisJun 04, 2026 P160295
A2623285Certificate of AnalysisJan 14, 2026 P160295
A2623304Certificate of AnalysisJan 14, 2026 P160295
A2623305Certificate of AnalysisJan 14, 2026 P160295
A2623320Certificate of AnalysisJan 14, 2026 P160295
G2510586Certificate of AnalysisJun 06, 2025 P160295
G2510585Certificate of AnalysisJun 06, 2025 P160295
A2607063Certificate of AnalysisJun 06, 2025 P160295
G2510583Certificate of AnalysisJun 06, 2025 P160295
G2510582Certificate of AnalysisJun 06, 2025 P160295
K2504761Certificate of AnalysisJul 04, 2024 P160295
A2609064Certificate of AnalysisJul 04, 2024 P160295
A2515105Certificate of AnalysisAug 05, 2022 P160295
A2506236Certificate of AnalysisAug 05, 2022 P160295
I2214257Certificate of AnalysisAug 05, 2022 P160295
I2214258Certificate of AnalysisAug 05, 2022 P160295
I2214259Certificate of AnalysisAug 05, 2022 P160295
I2214260Certificate of AnalysisAug 05, 2022 P160295
A2429377Certificate of AnalysisAug 05, 2022 P160295
E2306024Certificate of AnalysisAug 10, 2021 P160295

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Chemical and Physical Properties
Boil Point(°C)178 °C/4 mmHg
Melt Point(°C)71.0-75.0℃
Molecular Weight212.240 g/mol
XLogP32.700
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass212.084 Da
Monoisotopic Mass212.084 Da
Topological Polar Surface Area26.300 Ų
Heavy Atom Count16
Formal Charge0
Complexity213.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Xinyuan Xu, Jinqiang Zhang, Hong Wu, Lei Shi, Jie Zhang, Kuan Ding, Shu Zhang, Shuaijun Wang, Shaobin Wang, Hongqi Sun.  (2023)  Effect of the Proton Transfer Pathway on Selective Photoreforming of Lignin Models for Target Products Enabled by Sulfur Vacancy Engineering on Chalcogenide Nanosheets.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.3c00827]
2. Gao Die, Zhu Qingqing, Liu Peng, Zhou Qing, Cheng Xiujie, Liu Li, Xu Junli, Lu Xingmei.  (2023)  Efficient Pretreatment of Corn Straw with Ionic Liquid Composite System.  Journal of Inorganic and Organometallic Polymers and Materials,  33  (7): (2000-2012).  [PMID:] [10.1007/s10904-023-02623-x]
3. Jun Deng, Chi Zhou, Yue Yang, Bing Nan, Lin Dong, Lingchao Cai, Lina Li, Zhu-Jun Wang, Xiaofei Yang, Zupeng Chen.  (2023)  Visible-light-driven selective cleavage of CC bonds in lignin model substrates using carbon nitride-supported ruthenium single-atom catalyst.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.142282]
4. Xie Chao, Lin Longfei, Huang Liang, Wang Zixin, Jiang Zhiwei, Zhang Zehui, Han Buxing.  (2021)  Zn-Nx sites on N-doped carbon for aerobic oxidative cleavage and esterification of C(CO)-C bonds.  Nature Communications,  12  (1): (1-12).  [PMID:34376654] [10.1038/s41467-021-25118-0]
5. Feng Chen, Xuebin Lin, Wei Chen, Na Wen, Yanqiao Jin.  (2024)  Double core–shell hollow nanocage CuO@Co3O4 for the selective hydrogenolysis of C–O bonds of lignin without external hydrogen.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.152002]
6. Yudong Guo, Xiya Chen, Yuxin Liu, Zhenjun Chen, Peiyuan Guo, Dongxiang Luo, Menglong Zhang, Xiao Liu.  (2024)  Inorganic–Organic Dual-Ligand-Regulated Photocatalysis of CdS@ZnxCd1–xS@ZnS Quantum Dots for Lignin Valorization.  ACS Applied Materials & Interfaces,      [PMID:38419339] [10.1021/acsami.3c18957]
7. Yun Tian, Mengqiao Gao, Zhiyang Tang, Fukun Li, Qiang Zeng, Jinxing Long, Xuehui Li.  (2024)  In-situ generated hydrogen for selective hydrogenolysis of lignin catalyzed by Mg-Al mixed oxides with nested Ni nanoparticles.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2024.115833]
8. Zifan Wu, Yacong Deng, Fengyu Tian, Yidi Wang, Na Fan, Guangzheng Sun, Yichuan Li, Yuan Pan, Bin Liu, Bin Dong, Han Hu, Yongming Chai.  (2025)  N-doped biochar supported Ni-Co alloy catalyst for efficient hydrocracking of enzymatic hydrolysis lignin to monophenols in water.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159424]
9. Fa-Peng Wu, Le-Le Qiu, Yun-Peng Zhao, Zong-Pin Fu, Jing Liang, Jian Xiao, Jian Li, Fang-Jing Liu, Jing-Pei Cao.  (2024)  Self-hydrogen transfer hydrogenolysis of β-O-4 bonds in lignin model compounds over NiCu/Al2O3 catalyst.  FUEL,      [PMID:] [10.1016/j.fuel.2024.132094]
10. Liu Guangyong, Lu Yumiao, Lu JunFeng, Wang Yanlei, Liang Shijing, He Hongyan, Jiang Lilong.  (2023)  Ionic liquid-trimetallic electrocatalytic system for C-O bond cleavage in lignin model compounds and lignin under ambient conditions.  Nano Research,      [PMID:] [10.1007/s12274-023-6086-z]
11. Shanshuai Chen, Qiqi Lu, Wanying Han, Puxiang Yan, Hongliang Wang, Wanbin Zhu.  (2020)  Insights into the oxidation–reduction strategy for lignin conversion to high-value aromatics.  FUEL,      [PMID:] [10.1016/j.fuel.2020.119333]
12. Jifang Zhang, Chengcheng Suo, Xinchi Hao, Xingyu Zhu, Yiheng Zhuang, Cunyuan Hu, Wei Li, Sha Luo, Bing Tian, Chunhui Ma, Shouxin Liu.  (2025)  Radical-mediated Cα-Cβ cleavage by ZnIn2S4-based heterojunction materials in photo-electro-catalysis.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2025.116189]
13. Qibin Zeng, Yuancai Lv, Meiyan Shi, Ting Pan, Yunhe Xie, Yifan Liu, Minghua Liu.  (2025)  Synergistic interaction between Ni single atoms and nanoparticles for selective cleavage of C-O bonds in lignin without external hydrogen.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2025.116565]
14. Feng Chen, Xiang Xia, Wei Chen, Wei Liu, Xinxin Liao, Lei Xiong, Yanqiao Jin.  (2026)  Highly efficient sea urchin-like N-doped CuCo bimetallic catalyst for selective cleavage of α-O-4 linkage in lignin.  Journal of Environmental Chemical Engineering,  14  (3): (122374).  [PMID:] [10.1016/j.jece.2026.122374]
15. Shinjae Lee, Hayoung Jeong, Hyungjin Choi, Chaewon Lee, Donghyeon Kim, Eonu Nam, Na Hye Kim, Hyeongeon Lee, Jeong Woo Han, Kwangjin An.  (2026)  Self-hydrogen supplied reductive catalytic fractionation of lignocellulose over Ru1/Mg(OH)2 for high-yield production of lignin-derived monomers.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.179504]
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