4-Methylumbelliferyl phosphate disodium salt - ≥98% , CAS No.22919-26-2

CAS: 22919-26-2 Cat. No.: M168797 Molecular Weight: 300.11 (anhydrous)

GRADE & PURITY ≥98%

Synonyms

SCHEMBL380623 | Sodium 4-methyl-2-oxo-2H-chromen-7-yl phosphate | 4-Methylumbelliferyl phosphate disodium salt, phosphatase substrate | AKOS015913006 | disodium;(4-methyl-2-oxochromen-7-yl) phosphate | Disodium 4-methylumbelliferyl phosphate | 4-Methylumb

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Fluorogenic substrate for phosphatases.

Specifications

Synonyms

SCHEMBL380623 | Sodium 4-methyl-2-oxo-2H-chromen-7-yl phosphate | 4-Methylumbelliferyl phosphate disodium salt, phosphatase substrate | AKOS015913006 | disodium;(4-methyl-2-oxochromen-7-yl) phosphate | Disodium 4-methylumbelliferyl phosphate | 4-Methylumb

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Suitable as a fluorogenic substrate for phosphatases. Fluorescence: λ ex 319\xa0nm; λ em 384\xa0nm (pH 9.0); λ ex 360\xa0nm; λ em 449\xa0nm (Reaction product).

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504756005
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756005
• Canonical Smiles: CC1=CC(=O)OC2=C1C=CC(=C2)OP(=O)([O-])[O-].[Na+].[Na+]
• IUPAC Name: disodium;(4-methyl-2-oxochromen-7-yl) phosphate
• InChIKey: WUUDJQVNZPEPKN-UHFFFAOYSA-L
• INCHI: 1S/C10H9O6P.2Na/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14;;/h2-5H,1H3,(H2,12,13,14);;/q;2*+1/p-2
• Isomeric SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)OP(=O)([O-])[O-].[Na+].[Na+]
• Molecular Weight: 300.11 (anhydrous)
• Reaxy-Rn: 11226375
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11226375&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Class Coumarins and derivatives

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Class: Coumarins and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Coumarins and derivatives
• Alternative Parents: Aryl phosphomonoesters 1-benzopyrans Pyranones and derivatives Benzenoids Heteroaromatic compounds Lactones Oxacyclic compounds Organooxygen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Coumarin - Aryl phosphate - Aryl phosphomonoester - Benzopyran - 1-benzopyran - Pyranone - Organic phosphoric acid derivative - Phosphoric acid ester - Benzenoid - Pyran - Heteroaromatic compound - Lactone - Oxacycle - Organic alkali metal salt - Organoheterocyclic compound - Organic oxygen compound - Organic salt - Organooxygen compound - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 300.110 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 299.978 Da
• Monoisotopic Mass: 299.978 Da
• Topological Polar Surface Area: 98.700 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 386.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Chengli Xie, Longcheng Gong, Tong Xu, Lianzhe Hu, Zhining Xia, Min Wang.  (2025)  Heterovalent Co Doping Boosts the Phosphatase-like Activity of UiO-66-NH2 for Ultrasensitive Fluorescence Immunoassay of CEA.  ANALYTICAL CHEMISTRY,      [PMID:41428200] [10.1021/acs.analchem.5c04648]