6-Chloronicotinic Acid - 10mM in DMSO , CAS No.5326-23-8

CAS: 5326-23-8 Cat. No.: C661121 Molecular Weight: 157.55 Beilstein Registry Number: 115993 EC Number: 226-201-5
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GRADE & PURITY 10mM in DMSO
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
1ml
C661121-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. 6-CNA is a degradation product of neonicotinoid insecticides imidacloprid and acetamiprid and is known to appear in different environmental matrices.The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples.

Specifications

Specifications & Purity
10mM in DMSO
Storage
Room temperature
Shipped In
Normal
Names and Identifiers
Isomeric SMILES C1=CC(=NC=C1C(=O)O)Cl
WGK Germany 3
Molecular Weight 157.55
Beilstein 115993
Reaxy-Rn 115993
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=115993&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
NAPRT Tchem Nicotinate phosphoribosyltransferase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySoluble in Methanol,Ether,Ethanol; Slightly soluble in Chloroform,Benzene
Citations of This Product
References
1. Jingwen Zhang, Junning Liu, Yuheng Wang, Yong Wang, Ruiqin Yang, Xinyang Zhou.  (2023)  Simultaneous determination of ten neonicotinoid insecticides and a metabolite in human whole blood by QuEChERS coupled with UPLC-Q Exactive orbitrap high-resolution mass spectrometry.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,      [PMID:37059012] [10.1016/j.jchromb.2023.123689]
2. Shi Zhoukun, Dong Weiliang, Xin Fengxue, Liu Jiawei, Zhou Xinhai, Xu Fanli, Lv Ziyao, Ma Jiangfeng, Zhang Wenming, Fang Yan, Jiang Min.  (2018)  Characteristics and metabolic pathway of acetamiprid biodegradation by Fusarium sp. strain CS-3 isolated from soil.  BIODEGRADATION,  29  (6): (593-603).  [PMID:30259232] [10.1007/s10532-018-9855-8]
3. Dong Li, Chunran Zhou, Shuai Wang, Zhan Hu, Jia Xie, Canping Pan, Ranfeng Sun.  (2023)  Imidacloprid-induced stress affects the growth of pepper plants by disrupting rhizosphere-plant microbial and metabolite composition.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:37437628] [10.1016/j.scitotenv.2023.165395]
4. Mengling Tu, Wen Ma, Jia Chen, Yunxiao Zhu, Yang Liu, Xiaoli Ni, Xianjiang Li.  (2025)  Machine learning driven decoding of impurity fingerprint in imidacloprid material.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113399]
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