Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
8-Aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. The reaction of 8-aminoquinoline with chromium (III), manganese (II), iron (II) and (III), cobalt (II), nickel (II), copper (II), zinc (II), cadmium (II) and platinum (II) salts has been studied.
8-Aminoquinoline has been used in: preparation of base-stabilized terminal borylene complex of osmium spectrophotometric determination of bivalent palladium
| Pubchem Sid | 488181314 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181314 |
| Canonical Smiles | C1=CC2=C(C(=C1)N)N=CC=C2 |
| IUPAC Name | quinolin-8-amine |
| InChIKey | WREVVZMUNPAPOV-UHFFFAOYSA-N |
| INCHI | 1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2 |
| Isomeric SMILES | C1=CC2=C(C(=C1)N)N=CC=C2 |
| WGK Germany | 3 |
| RTECS | VA9627000 |
| Molecular Weight | 144.17 |
| Beilstein | 114474 |
| Reaxy-Rn | 114474 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=114474&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Quinolines and derivatives |
| Subclass | Aminoquinolines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Aminoquinolines and derivatives |
| Alternative Parents | Pyridines and derivatives Benzenoids Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Aminoquinoline - Benzenoid - Pyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as aminoquinolines and derivatives. These are organic compounds containing an amino group attached to a quinoline ring system. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Mar 08, 2023 | A105027 | |
| Certificate of Analysis | Nov 21, 2022 | A105027 | |
| Certificate of Analysis | Nov 21, 2022 | A105027 | |
| Certificate of Analysis | Nov 21, 2022 | A105027 | |
| Certificate of Analysis | Nov 21, 2022 | A105027 | |
| Certificate of Analysis | Nov 21, 2022 | A105027 | |
| Certificate of Analysis | Jun 15, 2022 | A105027 | |
| Certificate of Analysis | Jun 15, 2022 | A105027 |
| Solubility | Soluble in water. |
|---|---|
| Sensitivity | Air Sensitive |
| Boil Point(°C) | 174 °C/26 mmHg |
| Melt Point(°C) | 62-65°C |
| Molecular Weight | 144.170 g/mol |
| XLogP3 | 1.800 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 144.069 Da |
| Monoisotopic Mass | 144.069 Da |
| Topological Polar Surface Area | 38.900 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 136.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yixuan Yao, Fudong Zeng, Liangqiang Wu, Shuo Xing, Qingbiao Yang, Yaoxian Li. (2023) A novel “on–off–on” near-infrared fluorescent probe for Cu2+ and S2− continuous detection based on dicyanoisoflurone derivatives, and its application in bacterial imaging. Analytical Methods, 15 (40): (5329-5340). [PMID:37791492] [10.1039/D3AY01339A] |
| 2. Fan Wu, Hao Li, Yang Pan, Yingjia Wang, Yonghui Sun, Jianming Pan. (2023) Sustainable utilization of palladium from industrial catalytic waste by a smart magnetic nano stirring robot. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.123536] |
| 3. Zang Yu, Gao Shan, Jing Boyu, Sun Hong, Wang Jianjun, Liu Jiao, Miao Fengjuan, Xu Liang. (2022) Synthesis of Pd/conjugated microporous polymer heterogeneous catalysts via imine groups and high catalytic efficiency on Suzuki–Miyaura coupling reaction. JOURNAL OF MATERIALS SCIENCE, 58 (1): (170-185). [PMID:] [10.1007/s10853-022-08032-8] |
| 4. Fan Wu, Hao Li, Yang Pan, Yonghui Sun, Jianming Pan. (2022) Bioinspired construction of magnetic nano stirring rods with radially aligned dual mesopores and intrinsic rapid adsorption of palladium. JOURNAL OF HAZARDOUS MATERIALS, [PMID:36099737] [10.1016/j.jhazmat.2022.129917] |
| 5. Selvaraj Muthusamy, Siqi Yin, Kanagaraj Rajalakshmi, Suci Meng, Dongwei Zhu, Meng Xie, Jimin Xie, Rathna Silviya Lodi, Yuanguo Xu. (2022) Development of a quinoline-derived turn-on fluorescent probe for real time detection of hydrazine and its applications in environment and bioimaging. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2022.110618] |
| 6. Kanagaraj Rajalakshmi, Selvaraj Muthusamy, Yun-Sik Nam, Yujun Li, Kang-Bong Lee, Yuanguo Xu. (2021) A new recognition moiety diphenylborinate in the detection of pyruvate via Lewis acid/base sensing pathway and its bioimaging applications. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:34653848] [10.1016/j.saa.2021.120457] |
| 7. Selvaraj Muthusamy, Long Zhao, Kanagaraj Rajalakshmi, Dongwei Zhu, Shengjun Wang, John Mack, Kang-Bong Lee, Long Zhang, Weihua Zhu. (2021) Quantitative Hg2+ detection via forming three coordination complexes using a lysosome targeting quinoline - Fisher aldehyde fluorophore. TALANTA, [PMID:34635264] [10.1016/j.talanta.2021.122884] |
| 8. Brian Musikavanhu, Selvaraj Muthusamy, Dongwei Zhu, Zhaoli Xue, Qian Yu, Choonzo N. Chiyumba, John Mack, Tebello Nyokong, Shengjun Wang, Long Zhao. (2021) A simple quinoline-thiophene Schiff base turn-off chemosensor for Hg2+ detection: spectroscopy, sensing properties and applications. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:34482149] [10.1016/j.saa.2021.120338] |
| 9. Selvaraj Muthusamy, Long Zhao, Kanagaraj Rajalakshmi, Dongwei Zhu, Rodah Soy, John Mack, Tebello Nyokong, Shengjun Wang, Kang-Bong Lee, Weihua Zhu. (2021) Turn-on detection of cysteine by a donor-acceptor type quinoline fluorophore: Exploring the sensing strategy and performance in bioimaging. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2021.109556] |
| 10. Xinyu Wang, Zhuo Li, Jiaojiao Nie, Liangqiang Wu, Weihong Chen, Shaolong Qi, Hai Xu, Jianshi Du, Yaming Shan, Qingbiao Yang. (2021) A novel hydrophilic fluorescent probe for Cu2+ detection and imaging in HeLa cells. RSC Advances, 11 (17): (10264-10271). [PMID:35423512] [10.1039/D0RA09894A] |
| 11. Selvaraj Muthusamy, Kanagaraj Rajalakshmi, Qingxiang Xu, Yan Chen, Long Zhao, Weihua Zhu. (2020) An azido coumarin-quinoline conjugated fluorogenic dye: Utilizing amide-iminol tautomerism for H2S detection in live MCF-7 cells. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32387916] [10.1016/j.saa.2020.118345] |
| 12. Jian Lu, Yingying Qin, Chao Yu, Xinyu Lin, Minjia Meng, Yongsheng Yan, Hougang Fan, Yilin Wu, Chunxiang Li. (2019) Stable, regenerable and 3D macroporous Pd (II)-imprinted membranes for efficient treatment of electroplating wastewater. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2019.116220] |
| 13. Bing Zhang, Shixing Wang, Likang Fu, Libo Zhang. (2018) Synthesis and Evaluation of 8-Aminoquinoline-Grafted Poly(glycidyl methacrylate) for the Recovery of Pd(II) from Highly Acidic Aqueous Solutions. Polymers, 10 (4): (437). [PMID:30966472] [10.3390/polym10040437] |
| 14. Chen Yalin, Mei Tao, Chen Yi, Wang Jianying, Li Jinhua, Wang Xianbao. (2017) 8-aminoquinoline functionalized graphene oxide for simultaneous determination of guanine and adenine. JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 21 (5): (1357-1364). [PMID:] [10.1007/s10008-016-3492-0] |
| 15. Wei Zhang, Min Zhu, Feng Wang, Danhui Cao, Jennifer Jin Ruan, Weike Su, Benfang Helen Ruan. (2016) Mono-sulfonated tetrazolium salt based NAD(P)H detection reagents suitable for dehydrogenase and real-time cell viability assays. ANALYTICAL BIOCHEMISTRY, [PMID:27387057] [10.1016/j.ab.2016.06.026] |
| 16. Yi Pan, Yupeng Shi, Zhihua Chen, Junying Chen, Mengfei Hou, Zhanpeng Chen, Cheuk-Wing Li, Changqing Yi. (2016) Design of Multiple Logic Gates Based on Chemically Triggered Fluorescence Switching of Functionalized Polyethylenimine. ACS Applied Materials & Interfaces, [PMID:27007856] [10.1021/acsami.6b02080] |
| 17. Zhaomin Zhang, Yupeng Shi, Yi Pan, Xin Cheng, Lulu Zhang, Junying Chen, Mei-Jin Li, Changqing Yi. (2014) Quinoline derivative-functionalized carbon dots as a fluorescent nanosensor for sensing and intracellular imaging of Zn2+. Journal of Materials Chemistry B, 2 (31): (5020-5027). [PMID:32261835] [10.1039/C4TB00677A] |
| 18. Xin Tian, Zhengping Dong, Rou Wang, Jiantai Ma. (2013) A quinoline group modified Fe3O4@SiO2 nanoparticles for sequential detection of Zn2+ and hydrogen sulfide in aqueous solution and its logic behavior. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2013.03.124] |