8-Azaadenosine - ≥98%(HPLC) , CAS No.10299-44-2

CAS: 10299-44-2 Cat. No.: A288533 Molecular Weight: 268.23
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
(2R,3R,4S,5R)-2-{7-amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolane-3,4-diol | 3-?-D-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine | 8-Azaadenosine | 8-Aza-adenosine | Q27105620 | HY-115686 | 3-beta-D-Ribofuranosyl-3H-1,2,
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
A288533-5mg
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$96.90
10mg
A288533-10mg
3

$147.90

$221.90
Save $74.00 (33.35%)
50mg
A288533-50mg
2

$543.90

$815.90
Save $272.00 (33.34%)
100mg
A288533-100mg
2

$870.90

$1,306.90
Save $436.00 (33.36%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
(2R, 3R, 4S, 5R)-2-{7-amino-3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl}-5-(hydroxymethyl)oxolane-3, 4-diol | 3-?-D-Ribofuranosyl-3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-7-amine | 8-Azaadenosine | 8-Aza-adenosine | Q27105620 | HY-115686 | 3-beta-D-Ribofuranosyl-3H-1, 2,
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restoreslet-7and inhibits leukemia stem cells self-renewalin vitro.
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesC1=NC(=C2C(=N1)N(N=N2)C3C(C(C(O3)CO)O)O)N
IUPAC Name(2R,3R,4S,5R)-2-(7-aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChIKeyOAUKGFJQZRGECT-UUOKFMHZSA-N
INCHI1S/C9H12N6O4/c10-7-4-8(12-2-11-7)15(14-13-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H2,10,11,12)/t3-,5-,6-,9-/m1/s1
Isomeric SMILES C1=NC(=C2C(=N1)N(N=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N
Molecular Weight 268.23
Reaxy-Rn 1226020
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1226020&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassCarbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Glycosyl compounds
Direct ParentGlycosylamines
Alternative Parents Pentoses  Triazolopyrimidines  Aminopyrimidines and derivatives  Imidolactams  Triazoles  Tetrahydrofurans  Heteroaromatic compounds  Secondary alcohols  Oxacyclic compounds  Azacyclic compounds  Primary amines  Primary alcohols  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents N-glycosyl compound - Pentose monosaccharide - Triazolopyrimidine - Aminopyrimidine - Monosaccharide - Pyrimidine - Imidolactam - Azole - Heteroaromatic compound - 1,2,3-triazole - Triazole - Tetrahydrofuran - Secondary alcohol - Organoheterocyclic compound - Azacycle - Oxacycle - Primary amine - Primary alcohol - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Amine - Alcohol - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as glycosylamines. These are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether).
External Descriptors N-glycosyl compound
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ADA Tclin Adenosine deaminase (129 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Bos taurus (956 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
G2320315Certificate of AnalysisMay 09, 2026 A288533
G2320316Certificate of AnalysisMay 09, 2026 A288533
G2320319Certificate of AnalysisMay 09, 2026 A288533
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 26.82, Max Conc. mM: 100
SensitivityMoisture sensitive
Molecular Weight268.230 g/mol
XLogP3-2.200
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count2
Exact Mass268.092 Da
Monoisotopic Mass268.092 Da
Topological Polar Surface Area152.000 Ų
Heavy Atom Count19
Formal Charge0
Complexity336.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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