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· · COA & SDS available for every product · Same-day shipping on in-stock items A66 - ≥98% , CAS No.1166227-08-2
Synonyms
AKOS025293511 | BDBM50042922 | CHEBI:91449 | C71541 | SMR004702785 | s2636 | SCHEMBL14833311 | A66, >=98% (HPLC) | BA41291 | A66;CCT128930 | AC-33133 | EX-A1124 | (S)-N1-(2-(tert-butyl)-4'-methyl-[4,5'-bithiazol]-2'-yl)pyrrolidine-1,2-dicarboxamide | AS-7
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
AKOS025293511 | BDBM50042922 | CHEBI:91449 | C71541 | SMR004702785 | s2636 | SCHEMBL14833311 | A66, >=98% (HPLC) | BA41291 | A66;CCT128930 | AC-33133 | EX-A1124 | (S)-N1-(2-(tert-butyl)-4'-methyl-[4, 5'-bithiazol]-2'-yl)pyrrolidine-1, 2-dicarboxamide | AS-7
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Potent and selective PI 3-kinase p110αinhibitor (IC50= 32 nM). Exhibits >100-fold selectivity for p110αover other PI 3-kinase isoforms. Inhibits Akt signaling and tumor growth in SK-OV-3 xenografts in mice.
A66 is a potent and highly selective inhibitor o
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504770203 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504770203 Canonical Smiles CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CSC(=N3)C(C)(C)C IUPAC Name (2S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide InChIKey HBPXWEPKNBHKAX-NSHDSACASA-N INCHI 1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1 Isomeric SMILES CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CSC(=N3)C(C)(C)C PubChem CID 42636535 Molecular Weight 393.53
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
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Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Class Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Proline and derivatives Alternative Parents Alpha amino acid amides Pyrrolidinecarboxamides 2,4,5-trisubstituted thiazoles 2,4-disubstituted thiazoles Heteroaromatic compounds Ureas Primary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Proline or derivatives - Alpha-amino acid amide - 2,4,5-trisubstituted 1,3-thiazole - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Pyrrolidine-1-carboxamide - 2,4-disubstituted 1,3-thiazole - Azole - Heteroaromatic compound - Pyrrolidine - Thiazole - Primary carboxylic acid amide - Carbonic acid derivative - Carboxamide group - Urea - Organoheterocyclic compound - Azacycle - Organopnictogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organic nitrogen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as proline and derivatives. These are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 39.35, Max Conc. mM: 100 Molecular Weight 393.500 g/mol XLogP3 2.800 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 393.129 Da Monoisotopic Mass 393.129 Da Topological Polar Surface Area 158.000 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 556.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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