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· · COA & SDS available for every product · Same-day shipping on in-stock items AC 261066 - Moligand™, ≥98%(HPLC) , Agonist of Retinoic acid receptor-β, CAS No.870773-76-5, Agonist of Retinoic acid receptor-β
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
AKOS024457947 | SCHEMBL4598579 | LGF3F89BZP | 4-[4-(2-butoxyethoxy)-5-methyl-1,3-thiazol-2-yl]-2-fluorobenzoic acid | Q27074132 | BDBM50413272 | Benzoic acid, 4-[4-(2-butoxyethoxy)-5-methyl-2-thiazolyl]-2-fluoro- | 4-(4-(2-butoxyethoxy)-5-methylthiazol-2-
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
AKOS024457947 | SCHEMBL4598579 | LGF3F89BZP | 4-[4-(2-butoxyethoxy)-5-methyl-1, 3-thiazol-2-yl]-2-fluorobenzoic acid | Q27074132 | BDBM50413272 | Benzoic acid, 4-[4-(2-butoxyethoxy)-5-methyl-2-thiazolyl]-2-fluoro- | 4-(4-(2-butoxyethoxy)-5-methylthiazol-2-
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent RARβ2 agonist (pEC50= 8.1). Selective over RARβ1, RARαand RARγ(pEC50values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649.
Mechanism of action
Agonist of Retinoic acid receptor-β
Names and Identifiers Canonical Smiles CCCCOCCOC1=C(SC(=N1)C2=CC(=C(C=C2)C(=O)O)F)C IUPAC Name 4-[4-(2-butoxyethoxy)-5-methyl-1,3-thiazol-2-yl]-2-fluorobenzoic acid InChIKey HSAOETBFVAWNRP-UHFFFAOYSA-N INCHI 1S/C17H20FNO4S/c1-3-4-7-22-8-9-23-15-11(2)24-16(19-15)12-5-6-13(17(20)21)14(18)10-12/h5-6,10H,3-4,7-9H2,1-2H3,(H,20,21) Isomeric SMILES CCCCOCCOC1=C(SC(=N1)C2=CC(=C(C=C2)C(=O)O)F)C Molecular Weight 353.41 Reaxy-Rn 10286728 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10286728&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Benzoic acids and derivatives Intermediate Tree Nodes Halobenzoic acids and derivatives Direct Parent Halobenzoic acids Alternative Parents 2-halobenzoic acids Benzoic acids 1-carboxy-2-haloaromatic compounds 2,4,5-trisubstituted thiazoles Benzoyl derivatives Alkyl aryl ethers Fluorobenzenes Aryl fluorides Vinylogous halides Heteroaromatic compounds Dialkyl ethers Azacyclic compounds Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organofluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents 2-halobenzoic acid or derivatives - 2-halobenzoic acid - Halobenzoic acid - Benzoic acid - 2,4,5-trisubstituted 1,3-thiazole - Benzoyl - 1-carboxy-2-haloaromatic compound - Alkyl aryl ether - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Heteroaromatic compound - Vinylogous halide - Azole - Thiazole - Ether - Dialkyl ether - Carboxylic acid - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Organohalogen compound - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Hydrocarbon derivative - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as halobenzoic acids. These are benzoic acids carrying a halogen atom on the benzene ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 35.34, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 35.34, Max Conc. mM: 100 Molecular Weight 353.400 g/mol XLogP3 4.000 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 9 Exact Mass 353.11 Da Monoisotopic Mass 353.11 Da Topological Polar Surface Area 96.900 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 401.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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