10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Amantadine HCl (1-adamantanamine) is used to treat or prevent infections of the respiratory tract caused by a certain virus.
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:
| Isomeric SMILES | C1C2CC3CC1CC(C2)(C3)N.Cl |
|---|---|
| WGK Germany | 3 |
| RTECS | AU4375000 |
| Molecular Weight | 187.71 |
| Beilstein | 4198854 |
| Reaxy-Rn | 4198854 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4198854&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Solubility | Solubility (25°C) In vitro DMSO: 36 mg/mL (200.87 mM); Ethanol: 36 mg/mL (200.87 mM); Water: Insoluble; |
|---|---|
| Melt Point(°C) | >360°C |
| 1. Qiuhui Hu, Bo Zhang, Huiming Ren, Xiaoxuan Zhou, Chengbin He, Youqing Shen, Zhuxian Zhou, Hongjie Hu. (2023) Supramolecular metal-organic frameworks as host-guest nanoplatforms for versatile and customizable biomedical applications. Acta Biomaterialia, [PMID:37482147] [10.1016/j.actbio.2023.07.026] |
| 2. Lin Yuan, Lizhen Liu, Zhi Mi, Meng Chen, Yunfeng Bai, Jun Qin, Feng Feng. (2023) A ratiometric sensor based on dual-emission carbon dots sensitive detection of amaranth. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:37393669] [10.1016/j.saa.2023.123058] |
| 3. Yu Fang, Haiyan Cui, Xiaoqin Liang, Jianping Yu, Jianrong Wang, Guanghui Zhao. (2022) Quaternary Ammonium-Tethered Phenylboronic Acids Appended Supramolecular Nanomicelles as a Promising Bacteria Targeting Carrier for Nitric Oxide Delivery. Polymers, 14 (20): (4451). [PMID:36298029] [10.3390/polym14204451] |
| 4. Junlian Wang, Wen Xu, Jianguo Cui, Guodong Xu, Yufu Chen, Peilong Wang, Ziyong Chang. (2022) The role of β, γ, δ-substituent of dialkylphosphinic acids in HREE extraction and separation behaviors. JOURNAL OF RARE EARTHS, [PMID:] [10.1016/j.jre.2022.09.024] |
| 5. Yuan-Fu Ding, Jianwen Wei, Xingping Quan, Wenting Gu, Long Xi, Ying Zheng, Yonghua Zhao, Jingwei Luo, Shengke Li, Greta S.P. Mok, Ruibing Wang. (2022) Hyaluronic acid-based supramolecular medicine with polyamines sequestration capability for cooperative anti-psoriasis. CARBOHYDRATE POLYMERS, [PMID:36088007] [10.1016/j.carbpol.2022.119968] |
| 6. Jianhua He, Wenli Zhang, Xiaoju Zhou, Fengfei Xu, Jiahui Zou, Qiqi Zhang, Yi Zhao, Hongliang He, Hu Yang, Jianping Liu. (2022) Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery. Bioactive Materials, [PMID:35475030] [10.1016/j.bioactmat.2022.03.041] |
| 7. Pengfei Ren, Dandan Wei, Xin Ge, Faming Wang, Min Liang, Jidong Dai, Li Xu, Tianzhu Zhang. (2021) Injectable supramolecular hydrogels based on host–guest interactions with cell encapsulation capabilities. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2021.127338] |
| 8. Chen Zhongyin, Liao Tao, Wan Lihui, Kuang Ying, Liu Chang, Duan Junlin, Xu Xiangyu, Xu Ziqiang, Jiang Bingbing, Li Cao. (2021) Dual-stimuli responsive near-infrared emissive carbon dots/hollow mesoporous silica-based integrated theranostics platform for real-time visualized drug delivery. Nano Research, 14 (11): (4264-4273). [PMID:] [10.1007/s12274-021-3624-4] |
| 9. Hu Xiaohong, Gao Ziyu, Tan Huaping, Wang Huiming, Mao Xincheng, Pang Juan. (2019) An Injectable Hyaluronic Acid-Based Composite Hydrogel by DA Click Chemistry With pH Sensitive Nanoparticle for Biomedical Application. Frontiers in Chemistry, [PMID:31334222] [10.3389/fchem.2019.00477] |
| 10. Jiagen Li, Peng Liu. (2018) One-pot fabrication of pH/reduction dual-stimuli responsive chitosan-based supramolecular nanogels for leakage-free tumor-specific DOX delivery with enhanced anti-cancer efficacy. CARBOHYDRATE POLYMERS, [PMID:30241856] [10.1016/j.carbpol.2018.08.102] |
| 11. Guo-Feng Luo, Wei-Hai Chen, Qi Lei, Wen-Xiu Qiu, Yu-Xin Liu, Yin-Jia Cheng, Xian-Zheng Zhang. (2016) A Triple-Collaborative Strategy for High-Performance Tumor Therapy by Multifunctional Mesoporous Silica-Coated Gold Nanorods. ADVANCED FUNCTIONAL MATERIALS, 26 (24): (4339-4350). [PMID:] [10.1002/adfm.201505175] |
| 12. Kongchang Wei, Meiling Zhu, Yuxin Sun, Jianbin Xu, Qian Feng, Sien Lin, Tianyi Wu, Jia Xu, Feng Tian, Jiang Xia, Gang Li, Liming Bian. (2016) Robust Biopolymeric Supramolecular “Host−Guest Macromer” Hydrogels Reinforced by in Situ Formed Multivalent Nanoclusters for Cartilage Regeneration. MACROMOLECULES, [PMID:] [10.1021/acs.macromol.5b02527] |
| 13. Shixiang Feng, Xu Zhang, Yanxiang Liu. (2015) New insights into the primary phototransformation of acetaminophen by UV/H2O2: photo-Fries rearrangement versus hydroxyl radical induced hydroxylation. WATER RESEARCH, [PMID:25997748] [10.1016/j.watres.2015.05.008] |
| 14. Junlian Wang, Guang Chen, Shengming Xu, Linyan Li. (2015) Synthesis of novel nonsymmetric dialkylphosphinic acid extractants and studies on their extraction–separation performance for heavy rare earths. HYDROMETALLURGY, [PMID:] [10.1016/j.hydromet.2015.04.001] |
| 15. Zhao Zheng-bai, An Shuang-shuang, Xie Hai-jiao, Jiang Yong. (2014) Copolymerization and properties of multicomponent crosslinked hydrogels. CHINESE JOURNAL OF POLYMER SCIENCE, 33 (1): (173-183). [PMID:] [10.1007/s10118-015-1565-7] |
| 16. Yun-Dong Yin, Lei Yang, Xi-Tong Song, Jun Hu, Fang-Fang Chen, Ming Xu, Zhi-Yuan Gu. (2024) Determination of Acetylamantadine by γ-Cyclodextrin-Assisted α-HL Nanopore for Potential Cancer Prediagnosis. ANALYTICAL CHEMISTRY, [PMID:38738931] [10.1021/acs.analchem.3c04986] |
| 17. Tian-tian Yao, Jing Wang, Yun-fan Xue, Wei-jiang Yu, Qiang Gao, Lino Ferreira, Ke-Feng Ren, Jian Ji. (2019) A photodynamic antibacterial spray-coating based on the host–guest immobilization of the photosensitizer methylene blue. Journal of Materials Chemistry B, 7 (33): (5089-5095). [PMID:31432872] [10.1039/C9TB01069F] |
| 18. Simiao Yu, Chenyu Liu, Zhangrong Lou, Weihong Qiao. (2025) Sodium Alginate Silk Fibroin Hydrogel Loaded with Neural Stem Cells for Treatment of Cerebral Palsy. BIOMACROMOLECULES, [PMID:41031790] [10.1021/acs.biomac.5c01300] |
| 19. Zhongyu Li, Liping Pu, Delong Hou, Jun Yan, Qi Zeng, Yi Chen. (2025) Cross-linking Collagen Using Divalent Metal Ions. BIOMACROMOLECULES, [PMID:41258733] [10.1021/acs.biomac.5c01583] |
