Aminoguanidine Hydrochloride - 10mM in DMSO , CAS No.1937-19-5

CAS: 1937-19-5 Cat. No.: A422366 Molecular Weight: 110.55 EC Number: 217-707-7
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GRADE & PURITY 10mM in DMSO
Synonyms
A813665 | DTXCID7024405 | SMR000875337 | SY057364 | Carbazamidine HCl | Aminoguanidine (hydrochloride) | Aminoguanidine monohydrochloride | HY-B1041 | W-107714 | Aminoguanidine HCl | CCG-213626 | AC8587 | AMINOGUANIDINE HYDROCHLORIDE [MI] | PIMAGEDINE HYD
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
A422366-1ml
2

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Introduction

Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.

Product Usage

Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.

Specifications

Synonyms
A813665 | DTXCID7024405 | SMR000875337 | SY057364 | Carbazamidine HCl | Aminoguanidine (hydrochloride) | Aminoguanidine monohydrochloride | HY-B1041 | W-107714 | Aminoguanidine HCl | CCG-213626 | AC8587 | AMINOGUANIDINE HYDROCHLORIDE [MI] | PIMAGEDINE HYD
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Inhibits both constitutive and inducible nitric oxide synthetase. .Irreversible inhibitor of iNOS, displaying 26-fold selectivity over nNOS.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Canonical SmilesC(=NN)(N)N.Cl
IUPAC Name2-aminoguanidine;hydrochloride
InChIKeyUBDZFAGVPPMTIT-UHFFFAOYSA-N
INCHI1S/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H
Isomeric SMILES C(=NN)(N)N.Cl
WGK Germany 3
RTECS ME8430000
UN Number 3077
Packing Group III
Molecular Weight 110.55
Reaxy-Rn 7134851
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7134851&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassGuanidines
Intermediate Tree Nodes Not available
Direct ParentGuanidines
Alternative Parents Organopnictogen compounds  Organic chloride salts  Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Guanidine - Organopnictogen compound - Hydrocarbon derivative - Organic chloride salt - Organic salt - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as guanidines. These are compounds containing a guanidine moiety, with the general structure (R1R2N)(R3R4N)C=N-R5.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SensitivityAir & Moisture & heat & light sensitive
Melt Point(°C)162-166 °C
Molecular Weight110.550 g/mol
XLogP3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass110.036 Da
Monoisotopic Mass110.036 Da
Topological Polar Surface Area90.400 Ų
Heavy Atom Count6
Formal Charge0
Complexity41.600
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Documents & Articles
Citations of This Product
References
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