Azido-PEG₃-CH₂CO₂-NHS - ≥98% , CAS No.1092654-47-1

CAS: 1092654-47-1 Cat. No.: A596727 Molecular Weight: 330.3 PubChem CID: 121235813

GRADE & PURITY ≥98%

Synonyms

(2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetate | 12-Azido-3,6,9-trioxadodecan-1-oic acid-NHS-ester | 2,5-dioxopyrrolidin-1-yl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate | 2,5-dioxopyrrolidin-1-yl 2-{2-[2-(2-azidoethoxy)ethoxy]et

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Overview

Azido-PEG3-CH2CO2-NHS is a PEG derivative containing azide and NHS ester moieties. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. The azide group can react with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Specifications

Synonyms

(2, 5-dioxopyrrolidin-1-yl) 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetate | 12-Azido-3, 6, 9-trioxadodecan-1-oic acid-NHS-ester | 2, 5-dioxopyrrolidin-1-yl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate | 2, 5-dioxopyrrolidin-1-yl 2-{2-[2-(2-azidoethoxy)ethoxy]et

Specifications & Purity

≥98%

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: C1CC(=O)N(C1=O)OC(=O)COCCOCCOCCN=[N+]=[N-]
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetate
• InChIKey: XNHIEMNCUYXCFI-UHFFFAOYSA-N
• INCHI: 1S/C12H18N4O7/c13-15-14-3-4-20-5-6-21-7-8-22-9-12(19)23-16-10(17)1-2-11(16)18/h1-9H2
• PubChem CID: 121235813
• Molecular Weight: 330.3

Chemical and Physical Properties

• Solubility: Solubility in Water, DMSO, DCM, DMF
• Sensitivity: Light sensitive；Moisture sensitive
• Molecular Weight: 330.290 g/mol
• XLogP3: -0.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 13
• Exact Mass: 330.118 Da
• Monoisotopic Mass: 330.118 Da
• Topological Polar Surface Area: 106.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 448.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1