BMS-433771 dihydrochloride hydrate - ≥98% , CAS No.543700-67-0

CAS: 543700-67-0 Cat. No.: B650030 Molecular Weight: 468.38 EC Number: 110-727-6

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV) . BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV , with an average EC 50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease

In Vitro

BMS-433771 dihydrochloride hydrate has inhibitory against both A and B groups of RSV, with an average EC 50 of 20 nM. BMS-433771 dihydrochloride hydrate can inhibit viral F protein-induced membrane fusion. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

BMS-433771 dihydrochloride hydrate (p.o.; 1-200 mg/kg; single or bid 4 days) shows prophylactic efficacy via oral dosing，but has considerable pharmacodynamic differences between the two rodent models. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:EC50: 20 nM (RSV)

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV) . BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV , with an average EC 50 of 20 nM. BMS-433771 dihydrochloride hydr

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Molecular Weight: 468.38