Explore small molecules mapped to protein tyrosine kinase and receptor tyrosine kinase signaling for growth-factor biology and oncology research. This category supports focused screening and pathway studies around phosphorylation-driven signaling networks.
Protein Tyrosine Kinase/RTK
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- Insulin lispro (Standard)CAS: 133107-64-9 Formula: C257H383N65O77S6 Molecular Weight: 5807.63Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: I1451452View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
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- InChIKey
- WNRQPCUGRUFHED-DETKDSODSA-N
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- GW 583340 dihydrochlorideMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)◐ .Made to order · 8–12 wks Item #: G286712View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[(2-methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]quinazolin-4-amine;dihydrochloride
- SMILES
- CS(=O)(=O)CCNCC1=NC(=CS1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl.Cl
- InChIKey
- WIMITXDBYLKRKB-UHFFFAOYSA-N
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- Synonyms
- N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazoli...
- GSK1904529ACAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G127237View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
- InChIKey
- MOSKATHMXWSZTQ-UHFFFAOYSA-N
- InChI
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- Synonyms
- MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor ...
- NBI 31772CAS: 374620-70-9 Formula: C17H11NO7 Molecular Weight: 341.27● In Stock — US warehouse, ships to EU* Item #: N287388View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
- SMILES
- C1=CC(=C(C=C1C(=O)C2=NC(=CC3=CC(=C(C=C32)O)O)C(=O)O)O)O
- InChIKey
- ZCMFEWUYBFMLIN-UHFFFAOYSA-N
- InChI
- 1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
- Synonyms
- BDBM50106431 | DTXSID80741040 | UNII-7DYH3XNP6H | 1-[(3,4-Dioxocyclohexa-1,5-dien-1-yl)(hydroxy)methylidene]-6,7-dihy...
- AEE788 (NVP-AEE788), Vascular endothelial growth factor receptor 1 inhibitorCAS: 497839-62-0 Formula: C27H32N6 Molecular Weight: 440.58● In Stock — US warehouse, ships to EU* Item #: A126830View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
- InChIKey
- OONFNUWBHFSNBT-HXUWFJFHSA-N
- InChI
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- Synonyms
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[3,2-e]pyrimidin-4-amine | 7,9-Dimethyl-...
- GNF-2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G126166View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
- SMILES
- C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
- InChIKey
- WEVYNIUIFUYDGI-UHFFFAOYSA-N
- InChI
- 1S/C18H13F3N4O2/c19-18(20,21)27-14-6-4-13(5-7-14)25-16-9-15(23-10-24-16)11-2-1-3-12(8-11)17(22)26/h1-10H,(H2,22,26)(H,23,24,25)
- Synonyms
- HMS3265C23 | Bcr-abl inhibitor GNF-2 | HMS3333I20 | SB19395 | SW219739-1 | 3-[6-(4-trifluoromethoxyphenyl-amino)-pyri...
- NVP-ADW742CAS: 475488-23-4 Formula: C28H31N5O Molecular Weight: 453.58● In Stock — US warehouse, ships to EU* Item #: N126810View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(3-phenylmethoxyphenyl)-7-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
- InChIKey
- LSFLAQVDISHMNB-UHFFFAOYSA-N
- InChI
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- Synonyms
- 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | AS-56233 |...
- GW441756CAS: 504433-23-2 Formula: C17H13N3O Molecular Weight: 275.3● In Stock — US warehouse, ships to EU* Item #: G129825View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
- SMILES
- CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
- InChIKey
- NXNQLECPAXXYTR-LCYFTJDESA-N
- InChI
- 1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
- Synonyms
- GW441756 hydrochloride | 3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one | BRD-K04146668-...
- ZM306416 hydrochloride● In Stock — US warehouse, ships to EU* Item #: Z276165View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC.Cl
- InChIKey
- SCUXIROMWPQVJO-UHFFFAOYSA-N
- InChI
- 1S/C16H13ClFN3O2.ClH/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18;/h3-8H,1-2H3,(H,19,20,21);1H
- Synonyms
- 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazolinehydrochloride
- Foretinib (GSK1363089), Vascular endothelial growth factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: F127011View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-N'-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- SMILES
- COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
- InChIKey
- CXQHYVUVSFXTMY-UHFFFAOYSA-N
- InChI
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- Synonyms
- 81FH7VK1C4 | Foretinib [USAN:INN] | N-(3-FLUORO-4-((6-METHOXY-7-(3-(MORPHOLIN-4-YL)PROPOXY)QUINOLIN-4-YL)OXY) PHENYL)...
- Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitorCAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: L275009View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
- InChIKey
- UIARLYUEJFELEN-LROUJFHJSA-N
- InChI
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- Synonyms
- SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
- ZM 449829Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: Z275707View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-naphthalen-2-ylprop-2-en-1-one
- SMILES
- C=CC(=O)C1=CC2=CC=CC=C2C=C1
- InChIKey
- FOTCGZPFSUWZBN-UHFFFAOYSA-N
- InChI
- 1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
- Synonyms
- 1-(2-Naphthalenyl)-2-propen-1-one
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I compare when selecting Protein Tyrosine Kinase/RTK?
Within Protein Tyrosine Kinase/RTK, compare source and expression system, purity and the method used to measure it, specific activity, and buffer composition. In a sensitive assay the buffer can matter as much as the protein itself.
Which Protein Tyrosine Kinase/RTK subcategory should I start with?
Protein Tyrosine Kinase/RTK is organised into Ack1, Anaplastic lymphoma kinase (ALK), Bcr-Abl, BMX Kinase and BRK, and 27 further subcategories. Choose by the workflow step you are at rather than by molecule type — most workflows draw from more than one subcategory.
Which quality data should I review before ordering Protein Tyrosine Kinase/RTK?
Review the lot-specific Certificate of Analysis for the Protein Tyrosine Kinase/RTK product — purity, activity, and endotoxin — and confirm the buffer and any carrier protein. Carrier-free formats are worth specifying where downstream labelling or conjugation is planned. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What documentation is available for Protein Tyrosine Kinase/RTK?
Each Protein Tyrosine Kinase/RTK product page links a datasheet and a lot-specific Certificate of Analysis covering purity, activity, and storage. For lot reservations, bulk quantities, or documentation not shown, contact [email protected].