DNA Alkylator/Crosslinker

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  1. 1,6-Dibromo-1,6-dideoxy-D-mannitol
    CAS: 488-41-5 EC Number: 207-676-8 Formula: C6H12Br2O4 Molecular Weight: 307.97
    ● In Stock — US warehouse, ships to EU* Item #: D355800
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    IUPAC Name
    (2S,3S,4S,5S)-1,6-dibromohexane-2,3,4,5-tetrol
    SMILES
    C(C(C(C(C(CBr)O)O)O)O)Br
    InChIKey
    VFKZTMPDYBFSTM-KVTDHHQDSA-N
    InChI
    1S/C6H12Br2O4/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,9-12H,1-2H2/t3-,4-,5-,6-/m1/s1
    Synonyms
    DB13543 | D-Mannitol, 1,6-dibromo-1,6-dideoxy- | Myelobromol | EINECS 207-676-8 | MITOBRONITOL [WHO-DD] | NSC-94100 |...
  2. Bizelesin
    CAS: 129655-21-6 PubChem CID: 60794 Formula: C43H36Cl2N8O5 Molecular Weight: 815.7
    ◐ .Made to order · 8–12 wks Item #: B351163
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    IUPAC Name
    1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea
    SMILES
    CC1=CNC2=C(C=C3C(=C12)C(CN3C(=O)C4=CC5=C(N4)C=CC(=C5)NC(=O)NC6=CC7=C(C=C6)NC(=C7)C(=O)N8CC(C9=C1C(=CNC1=C(C=C98)O)C)CCl)CCl)O
    InChIKey
    FONKWHRXTPJODV-DNQXCXABSA-N
    InChI
    1S/C43H36Cl2N8O5/c1-19-15-46-39-33(54)11-31-37(35(19)39)23(13-44)17-52(31)41(56)29-9-21-7-25(3-5-27(21)50-29)48-43(58)49-26-4-6-28-22(8-26)10-30(51-28show more
    Synonyms
    1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]ure...
  3. Carboplatin
    CAS: 41575-94-4 EC Number: 255-446-0 Formula: C6H12N2O4Pt Molecular Weight: 371.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99.95% metals basis
    ● In Stock — US warehouse, ships to EU* Item #: C295384
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    IUPAC Name
    azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+)
    SMILES
    C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2]
    InChIKey
    VSRXQHXAPYXROS-UHFFFAOYSA-N
    InChI
    1S/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+2
    Synonyms
    AB01273939-01 | EN300-123065 | NSC758182 | NSC-758182 | STL451040 | Tox21_112586_1 | Carboplatinum | DTXCID201476080 ...
  4. Bendamustine
    CAS: 16506-27-7 EC Number: 680-659-4 Formula: C16H21Cl2N3O2 Molecular Weight: 358.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: B348790
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    IUPAC Name
    4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
    SMILES
    CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
    InChIKey
    YTKUWDBFDASYHO-UHFFFAOYSA-N
    InChI
    1S/C16H21Cl2N3O2/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23/h5-6,11H,2-4,7-10H2,1H3,(H,22,23)
    Synonyms
    AB01273966-01 | BDBM173621 | YTKUWDBFDASYHO-UHFFFAOYSA-N | 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]b...
  5. 2,4,6-Tris(dimethylamino)-1,3,5-triazine
    CAS: 645-05-6 EC Number: 211-428-4 PubChem CID: 2123 Formula: C9H18N6 Molecular Weight: 210.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: T124791
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    IUPAC Name
    2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
    SMILES
    CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C
    InChIKey
    UUVWYPNAQBNQJQ-UHFFFAOYSA-N
    InChI
    1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
    Synonyms
    Spectrum3_000951 | HMS2097N14 | KB-913 | SPBio_000754 | ENT-50852;RB-1515;WR-95704 | BSPBio_000912 | KBioGR_001388 | ...
  6. cis-Diammineplatinum dichloride
    CAS: 15663-27-1 EC Number: 239-733-8 Formula: H6Cl2N2Pt Molecular Weight: 300.1
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Pt,65%
    ● In Stock — US warehouse, ships to EU* Item #: D109812
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    Technical Identifiers
    SMILES
    N.N.Cl[Pt]Cl
    InChIKey
    LXZZYRPGZAFOLE-UHFFFAOYSA-L
    InChI
    1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
    Synonyms
    Cisplatin
  7. cis-Diammineplatinum dichloride
    CAS: 15663-27-1 EC Number: 239-733-8 Formula: H6Cl2N2Pt Molecular Weight: 300.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99.5%
    ● In Stock — US warehouse, ships to EU* Item #: C295225
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    Technical Identifiers
    SMILES
    N.N.Cl[Pt]Cl
    InChIKey
    LXZZYRPGZAFOLE-UHFFFAOYSA-L
    InChI
    1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
    Synonyms
    Cisplatin | cis-Dichlorodiammine platinum(II) | cis-Platinum(II) diammine dichloride | cis-Diammineplatinum(II) dichl...
  8. 1-Methyl-3-nitro-1-nitrosoguanidine(MNNG)
    CAS: 70-25-7 EC Number: 200-730-1 Formula: C2H5N5O3 Molecular Weight: 147.09
    ● In Stock — US warehouse, ships to EU* Item #: M105583
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    IUPAC Name
    1-methyl-3-nitro-1-nitrosoguanidine
    SMILES
    CN(C(=N)N[N+](=O)[O-])N=O
    InChIKey
    VZUNGTLZRAYYDE-UHFFFAOYSA-N
    InChI
    1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4)
    Synonyms
    MNNG | N-Nitroso-N'-nitro-N-methylguanidine | RCRA waste number U163 | 3-methyl-1-nitro-3-nitrosoguanidine | BSPBio_0...
  9. Busulfan-d8
    CAS: 116653-28-2 Formula: C6H6D8O6S2 Molecular Weight: 254.35
    ◐ .Made to order · 8–12 wks Item #: B345147
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    IUPAC Name
    (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate
    SMILES
    CS(=O)(=O)OCCCCOS(=O)(=O)C
    InChIKey
    COVZYZSDYWQREU-SQUIKQQTSA-N
    InChI
    1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3/i3D2,4D2,5D2,6D2
    Synonyms
    (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate | Busulphan-d8 | AKOS030241600 | Busulfex-d8...
  10. 2,4,6-Tris(dimethylamino)-1,3,5-triazine
    CAS: 645-05-6 EC Number: 211-428-4 PubChem CID: 2123 Formula: C9H18N6 Molecular Weight: 210.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T425266
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    IUPAC Name
    2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
    SMILES
    CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C
    InChIKey
    UUVWYPNAQBNQJQ-UHFFFAOYSA-N
    InChI
    1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
    Synonyms
    altretamine|645-05-6|HEXAMETHYLMELAMINE|Hexalen|Hexastat|Hemel|2,4,6-Tris(dimethylamino)-1,3,5-triazine|N2,N2,N4,N4,N...
  11. Bendamustine
    CAS: 16506-27-7 EC Number: 680-659-4 Formula: C16H21Cl2N3O2 Molecular Weight: 358.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B422048
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    IUPAC Name
    4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
    SMILES
    CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
    InChIKey
    YTKUWDBFDASYHO-UHFFFAOYSA-N
    InChI
    1S/C16H21Cl2N3O2/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23/h5-6,11H,2-4,7-10H2,1H3,(H,22,23)
    Synonyms
    AB01273966-01 | BDBM173621 | YTKUWDBFDASYHO-UHFFFAOYSA-N | 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]b...
  12. L-Tartaric Acid Di(N-succinimidyl) Ester
    CAS: 62069-75-4 Formula: C12H12N2O10 Molecular Weight: 344.23
    ● In Stock — US warehouse, ships to EU* Item #: B304175
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    IUPAC Name
    bis(2,5-dioxopyrrolidin-1-yl) 2,3-dihydroxybutanedioate
    SMILES
    C1CC(=O)N(C1=O)OC(=O)C(C(C(=O)ON2C(=O)CCC2=O)O)O
    InChIKey
    NXVYSVARUKNFNF-UHFFFAOYSA-N
    InChI
    1S/C12H12N2O10/c15-5-1-2-6(16)13(5)23-11(21)9(19)10(20)12(22)24-14-7(17)3-4-8(14)18/h9-10,19-20H,1-4H2
    Synonyms
    DST(disuccinimidyl tartrate) | 2,5-Pyrrolidinedione,1,1'-[(2,3-dihydroxy-1,4-dioxo-1,4-butanediyl)bis(oxy)]bis- | bis...
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Frequently Asked Questions

Which compounds are listed for DNA Alkylator/Crosslinker?
Compounds associated with DNA Alkylator/Crosslinker are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does DNA Alkylator/Crosslinker sit within Cell Cycle/DNA Damage?
DNA Alkylator/Crosslinker is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from DNA Alkylator/Crosslinker?
For compounds listed under DNA Alkylator/Crosslinker, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for DNA Alkylator/Crosslinker?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring DNA Alkylator/Crosslinker, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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