application：
CP-456773 sodium salt has been used :
In in vivo experiments to study the neuroprotective action of ketogenic diet.
To study the effect of inhibition of NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models.
To study the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants.
| Canonical Smiles | CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+] |
|---|---|
| IUPAC Name | sodium;1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylazanide |
| InChIKey | LFQQNXFKPNZRFT-UHFFFAOYSA-M |
| INCHI | 1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q;+1/p-1 |
| Isomeric SMILES | CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+] |
| Molecular Weight | 426.46 |
| Reaxy-Rn | 9463223 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9463223&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Indanes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indanes |
| Alternative Parents | Sulfonylureas Tertiary alcohols Sulfonyls Organosulfonic acids and derivatives Heteroaromatic compounds Furans Oxacyclic compounds Carbene-type 1,3-dipolar compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Aromatic alcohols |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Indane - Sulfonylurea - Furan - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Heteroaromatic compound - Sulfonyl - Tertiary alcohol - Oxacycle - Organic alkali metal salt - Organoheterocyclic compound - Organic 1,3-dipolar compound - Carbene-type 1,3-dipolar compound - Alcohol - Aromatic alcohol - Organic zwitterion - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as indanes. These are compounds containing an indane moiety, which consists of a cyclopentane fused to a benzene ring. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2214011 | Certificate of Analysis | Dec 19, 2024 | C287926 |
| C2214012 | Certificate of Analysis | Dec 19, 2024 | C287926 |
| C2214019 | Certificate of Analysis | Dec 19, 2024 | C287926 |
| C2214020 | Certificate of Analysis | Dec 19, 2024 | C287926 |
| C2214021 | Certificate of Analysis | Dec 19, 2024 | C287926 |
| Solubility | Solvent:water, Max Conc. mg/mL: 42.65, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 42.65, Max Conc. mM: 100 |
|---|---|
| Sensitivity | Sensitive to humidity, heat, air |
| Melt Point(°C) | 239 °C |
| Molecular Weight | 426.500 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 426.123 Da |
| Monoisotopic Mass | 426.123 Da |
| Topological Polar Surface Area | 106.000 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 690.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
