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· · COA & SDS available for every product · Same-day shipping on in-stock items Cytosine β-D-arabinofuranoside hydrochloride - 10mM in DMSO , CAS No.69-74-9
GRADE & PURITY 10mM in DMSO
Synonyms
CYTARABINE HYDROCHLORIDE|69-74-9|Cytosine arabinoside hydrochloride|Cytarabine HCl|1-beta-D-Arabinofuranosylcytosine hydrochloride|Cytarabine hydrochloride [USAN]|U-19920A|Cytarabine (hydrochloride)|Ara-C hydrochloride|Cytosar hydrochloride|Cytosine-1-bet
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
CYTARABINE HYDROCHLORIDE | 69-74-9 | Cytosine arabinoside hydrochloride | Cytarabine HCl | 1-beta-D-Arabinofuranosylcytosine hydrochloride | Cytarabine hydrochloride [USAN] | U-19920A | Cytarabine (hydrochloride) | Ara-C hydrochloride | Cytosar hydrochloride | Cytosine-1-bet
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway.Does not inhibit
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl IUPAC Name 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride InChIKey KCURWTAZOZXKSJ-JBMRGDGGSA-N INCHI 1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1 Isomeric SMILES C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl WGK Germany 3 Molecular Weight 279.68 Reaxy-Rn 25076248 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25076248&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Nucleosides, nucleotides, and analogues Class Pyrimidine nucleosides Subclass Not available Intermediate Tree Nodes Not available Direct Parent Pyrimidine nucleosides Alternative Parents Glycosylamines Pentoses Pyrimidones Aminopyrimidines and derivatives Imidolactams Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Azacyclic compounds Oxacyclic compounds Hydrochlorides Hydrocarbon derivatives Organic oxides Organopnictogen compounds Primary alcohols Primary amines Molecular Framework Aromatic heteromonocyclic compounds Substituents Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Aminopyrimidine - Pyrimidone - Hydropyrimidine - Monosaccharide - Pyrimidine - Imidolactam - Tetrahydrofuran - Heteroaromatic compound - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Primary amine - Primary alcohol - Organic oxide - Organooxygen compound - Organonitrogen compound - Amine - Alcohol - Organopnictogen compound - Organic oxygen compound - Hydrocarbon derivative - Hydrochloride - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Sensitivity Hygroscopic Molecular Weight 279.680 g/mol XLogP3 Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 2 Exact Mass 279.062 Da Monoisotopic Mass 279.062 Da Topological Polar Surface Area 129.000 Ų Heavy Atom Count 18 Formal Charge 0 Complexity 383.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 4 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
Documents & Articles Citations of This Product References 1. Andri Kurniawan Sutanto, Yuxin Xing, Tao Ding, Zhenqiang Wang, Kaiyao Sun, Dong Mo, Jixi Zhang, Kaiyong Cai. (2021) Hybrid mesoporous nanoparticles with highly integrated polydopamine for pH-responsive membrane permeation and drug delivery. Colloid and Interface Science Communications, [PMID: [10.1016/j.colcom.2021.100385 ]
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