D-Glucosamine sulphate - 10mM in DMSO , CAS No.29031-19-4

CAS: 29031-19-4 Cat. No.: D423022 Molecular Weight: 277.25 EC Number: 249-379-6

GRADE & PURITY 10mM in DMSO

Synonyms

D-Glucose, 2-amino-2-deoxy-, sulfate (salt) | EN300-7372813 | HY-N0487 | Glucosaminsulfat | (2R,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal sulfate | Glucosamine sulfate | CCG-267216 | Sulfuric acid--2-amino-2-deoxyhexose (1/1) | s3850 | Gevolox | AKOS0

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Glucosamine sulfate is an antiarthritic agent isolated from chitin.

Specifications

Synonyms

D-Glucose, 2-amino-2-deoxy-, sulfate (salt) | EN300-7372813 | HY-N0487 | Glucosaminsulfat | (2R, 3R, 4S, 5R)-2-Amino-3, 4, 5, 6-tetrahydroxyhexanal sulfate | Glucosamine sulfate | CCG-267216 | Sulfuric acid--2-amino-2-deoxyhexose (1/1) | s3850 | Gevolox | AKOS0

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Postranslational modification regulator. Inhibits N-glycosylation of certain proteins. Regulates TGF-β signaling. Downregulates HIF-1. Suppresses 5-HT-induced nociceptive responses. Shows analgesic effects in vivo. Orally active.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C(C(C(C(C(C=O)N)O)O)O)O.OS(=O)(=O)O
• IUPAC Name: (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;sulfuric acid
• InChIKey: FGNPLIQZJCYWLE-BTVCFUMJSA-N
• INCHI: 1S/C6H13NO5.H2O4S/c7-3(1-8)5(11)6(12)4(10)2-9;1-5(2,3)4/h1,3-6,9-12H,2,7H2;(H2,1,2,3,4)/t3-,4+,5+,6+;/m0./s1
• Isomeric SMILES: C([C@H]([C@H]([C@@H]([C@H](C=O)N)O)O)O)O.OS(=O)(=O)O
• Alternate CAS: 14307-02-9；14999-43-0
• Molecular Weight: 277.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Hexoses

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides
• Direct Parent: Hexoses
• Alternative Parents: Aminosaccharides Organic sulfuric acids Beta-hydroxy aldehydes 1,3-aminoalcohols Secondary alcohols Polyols Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hexose monosaccharide - Amino saccharide - Sulfuric acid - Beta-hydroxy aldehyde - Organic sulfuric acid or derivatives - 1,3-aminoalcohol - Secondary alcohol - Polyol - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Primary alcohol - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aldehyde - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 277.250 g/mol
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 5
• Exact Mass: 277.047 Da
• Monoisotopic Mass: 277.047 Da
• Topological Polar Surface Area: 207.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 223.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Fangjie Lu, Qinqin Wang, Mingyuan Zhu, Bin Dai.  (2023)  Deactivation and Regeneration of Nitrogen Doped Carbon Catalyst for Acetylene Hydrochlorination.  MOLECULES,  28  (3): (956).  [PMID:36770621] [10.3390/molecules28030956]

2. Hua Tian, Kaixin Zhu, Yang Jiang, Lin Wang, Wang Li, Zhifeng Yu, Cunqi Wu.  (2021)  Heterogeneous assembly of Ni–Co layered double hydroxide/sulfonated graphene nanosheet composites as battery-type materials for hybrid supercapacitors.  Nanoscale Advances,  3  (10): (2924-2933).  [PMID:36134181] [10.1039/D1NA00001B]

3. Wei Chen, Chi Wang, Yuying Gao, Yang Wu, Guomin Wu, Xiaowen Shi, Yumin Du, Hongbing Deng.  (2019)  Incorporating chitin derived glucosamine sulfate into nanofibers via coaxial electrospinning for cartilage regeneration.  CARBOHYDRATE POLYMERS,      [PMID:31826435] [10.1016/j.carbpol.2019.115544]

4. Shuai Ma, Li Zhang, Yang Wu, Wei Huang, Fangtian Liu, Mingguang Li, Yifeng Fan, Haibin Xia, Xianguo Wang, Xinzhi Li, Hongbing Deng.  (2024)  Glucosamine sulfate-loaded nanofiber reinforced carboxymethyl chitosan sponge for articular cartilage restoration.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39116561] [10.1016/j.jcis.2024.07.207]

5. Chen Li, Yalu Xin, Wei Gao, Yongping Chen.  (2025)  Enabling a Robust Long-Life Zinc-Iodine Flow Battery by Stabilizing the Zinc Anode in a Halide-Rich Electrolyte.  Small,      [PMID:40872987] [10.1002/smll.202508359]

6. Shujie Wang, Hetao Zhang, Zhongping Shao, Li Liu.  (2025)  Engineering microporous humins derived from glucosamine for CO2 adsorption.  BIOMASS & BIOENERGY,      [PMID:] [10.1016/j.biombioe.2025.108346]

7. Jiaojiao Yan, Haoxin Cai, Shuai Ma, Xin Wen, Ze Zhao, Shixin Wang, Yiming Qi, Jun Wu, Hongbing Deng.  (2026)  Hierarchically reinforced injectable chitosan-based hydrogels integrating mechanical-bioactive nanofibers and chondrogenic cues for articular cartilage reconstruction.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41506501] [10.1016/j.ijbiomac.2026.150133]