D-Valine - ≥98% , CAS No.640-68-6

CAS: 640-68-6 Cat. No.: V101067 Molecular Weight: 117.15 Beilstein Registry Number: 1721135 EC Number: 211-368-9
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
EINECS 211-368-9 | C06417 | DVA | (R)-alpha-Aminoisovaleric acid | NSC-20654 | AKOS006240045 | D-(-)-VALINE | H-D-Val-OH | NCGC00159470-02 | R-Valine | Thioethyl alcohol | AM82362 | (R)-2-Amino-3-methylbutyric acid | D-Val | A847288 | VALNEMULIN HYDROCHLO
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
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Status
Price
Qty
1g
V101067-1g
5
$9.90
5g
V101067-5g
4
$10.90
10g
V101067-10g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$11.90
25g
V101067-25g
8
$12.90
100g
V101067-100g
5

$15.90

$23.90
Save $8.00 (33.47%)
500g
V101067-500g
2

$77.90

$116.90
Save $39.00 (33.36%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

D-Valine is a selective inhibitor of cell proliferation. It inhibit cells that lack the enzyme D-amino acid oxidase. D-Valine has been shown to inhibit fibroblast growth while allowing selective growth of epithelial cells. L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.
An isomer of the essential amino acid L-Valine

Specifications

Synonyms
EINECS 211-368-9 | C06417 | DVA | (R)-alpha-Aminoisovaleric acid | NSC-20654 | AKOS006240045 | D-(-)-VALINE | H-D-Val-OH | NCGC00159470-02 | R-Valine | Thioethyl alcohol | AM82362 | (R)-2-Amino-3-methylbutyric acid | D-Val | A847288 | VALNEMULIN HYDROCHLO
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488184661
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184661
Canonical SmilesCC(C)C(C(=O)O)N
IUPAC Name(2R)-2-amino-3-methylbutanoic acid
InChIKeyKZSNJWFQEVHDMF-SCSAIBSYSA-N
INCHI1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
Isomeric SMILES CC(C)[C@H](C(=O)O)N
WGK Germany 3
RTECS YV9360000
Molecular Weight 117.15
Beilstein 1721135
Reaxy-Rn 506689
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=506689&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentValine and derivatives
Alternative Parents D-alpha-amino acids  Methyl-branched fatty acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Valine or derivatives - Alpha-amino acid - D-alpha-amino acid - Branched fatty acid - Methyl-branched fatty acid - Fatty acid - Fatty acyl - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as valine and derivatives. These are compounds containing valine or a derivative thereof resulting from reaction of valine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Other amino acids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeDateItem
C2515119Certificate of AnalysisApr 01, 2025 V101067
C2625147Certificate of AnalysisApr 01, 2025 V101067
F2108189Certificate of AnalysisMar 04, 2025 V101067
F2108192Certificate of AnalysisMar 04, 2025 V101067
D2530365Certificate of AnalysisJul 09, 2024 V101067
D2530366Certificate of AnalysisJul 09, 2024 V101067
E2508472Certificate of AnalysisJul 09, 2024 V101067
L2214547Certificate of AnalysisNov 09, 2022 V101067
L2214546Certificate of AnalysisNov 09, 2022 V101067
L2214545Certificate of AnalysisNov 09, 2022 V101067
L2214544Certificate of AnalysisNov 09, 2022 V101067
L2214543Certificate of AnalysisNov 09, 2022 V101067
L2214542Certificate of AnalysisNov 09, 2022 V101067
H2504034Certificate of AnalysisNov 09, 2022 V101067
E2512095Certificate of AnalysisNov 09, 2022 V101067
E2415060Certificate of AnalysisNov 09, 2022 V101067
E2308605Certificate of AnalysisNov 09, 2022 V101067
C2515121Certificate of AnalysisNov 09, 2022 V101067
J2219115Certificate of AnalysisOct 21, 2022 V101067
L1812106Certificate of AnalysisSep 21, 2022 V101067
D1813135Certificate of AnalysisFeb 18, 2022 V101067
K2209070Certificate of AnalysisMay 08, 2021 V101067
K2209071Certificate of AnalysisMay 08, 2021 V101067
B2317071Certificate of AnalysisMay 08, 2021 V101067
B2317052Certificate of AnalysisMay 08, 2021 V101067

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Chemical and Physical Properties
SolubilitySoluble in water (56 mg/ml at 20° C), Aqueous Acid, and 3N HCI. Insoluble in ethanol, and ether.
Specific Rotation[α]-27 ° (C=8, 6mol/L HCl)
Melt Point(°C)302-303°C
Molecular Weight117.150 g/mol
XLogP3-2.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass117.079 Da
Monoisotopic Mass117.079 Da
Topological Polar Surface Area63.300 Ų
Heavy Atom Count8
Formal Charge0
Complexity90.400
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai.  (2023)  Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.  Advanced Science,      [PMID:38072636] [10.1002/advs.202308362]
2. Li Gao, Piao Xu, Jiaoyan Ren.  (2023)  A sensitive and economical method for simultaneous determination of D/L- amino acids profile in foods by HPLC-UV: Application in fermented and unfermented foods discrimination.  FOOD CHEMISTRY,      [PMID:36628920] [10.1016/j.foodchem.2022.135382]
3. Shutong Yang, Liancheng Gu, Fangling Wu, Xinhua Dai, Fuxing Xu, Qiaoyu Li, Xiang Fang, Shaoning Yu, Chuan-Fan Ding.  (2022)  The chirality determination of amino acids by forming complexes with cyclodextrins and metal ions using ion mobility spectrometry, and a DFT calculation.  TALANTA,      [PMID:35272154] [10.1016/j.talanta.2022.123363]
4. Jun Zhang, Tingyang Xing, Min Zhang, Yunlong Zhou.  (2022)  Facile preparation of Cu2-xS supernanoparticles with an unambiguous SERS enhancement mechanism.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2021.134457]
5. Deng Jun, Wu Sai, Yao Mengyun, Gao Changyou.  (2016)  Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles.  Scientific Reports,  (1): (1-12).  [PMID:27531648] [10.1038/srep31595]
6. Jun Zhang, Kai Wu, Xiaoqing Gao, Min Zhang, Xin Zhou, Florian Bertram, Chen Shen, Yunlong Zhou.  (2024)  Achiral and chiral ligands synergistically harness chiral self-assembly of inorganics.  Science Advances,  10  (42):   [PMID:39423258] [10.1126/sciadv.ado5948]
7. Ding Junfeng, Wang Tianran, Lin Zhiqiang, Li Zhenyu, Yang Jiaxuan, Li Fujiang, Rong Yan, Chen Xuesi, He Chaoliang.  (2025)  Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response.  Nature Communications,  16  (1): (1-21).  [PMID:39890820] [10.1038/s41467-025-56137-w]
8. Lilan Tan, Wenrong Cai, Fangqin Wang, Junyao Li, Datong Wu, Yong Kong.  (2024)  Postsynthetic Modification Strategy for Constructing Electrochemiluminescence-Active Chiral Covalent Organic Frameworks Performing Efficient Enantioselective Sensing.  ANALYTICAL CHEMISTRY,      [PMID:38394220] [10.1021/acs.analchem.3c05887]
9. Zhou Mengyan, Zhang Zhihui, Zheng Qi, Yu Mingdi, Si Mengxu, Wu Sirui, Zhang Yanan, Ding Shushu, Fu Ding-Yi.  (2025)  Ratiometric fluorescence quantification of folic acid utilizing D-penicillamine-based carbon dots in conjunction with glutathione S-transferase-Au nanoclusters.  MICROCHIMICA ACTA,  192  (4): (1-13).  [PMID:40080078] [10.1007/s00604-025-07062-8]
10. Dan Zhao, Jingjing Huang, Juan Li, Xiao Ma, Fang Wang, Honglei Zhang, Jiaze Xie, Jian Sun, Chuanxia Chen.  (2023)  Ultrasensitive colorimetric and fluorescent dual-readout assay for D-penicillamine based on the chloride boosted oxidative ability of copper ions.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.108535]
11. Simin Zhang, Xiangfeng Chen, Yaping Shi, Xiangyu Zhu, Zongwei Cai.  (2026)  Soft-Chain-Induced Ultrahigh-Resolution Chiral Separation of Amino Acids via Bimetallic Immobilization in MALDI-TIMS-MS.  ANALYTICAL CHEMISTRY,      [PMID:41701523] [10.1021/acs.analchem.5c07869]
Solution Calculators
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