Deferoxamine mesylate (Ba 33112) - 10mM in DMSO , Iron chelating agent, CAS No.138-14-7, Iron chelating agent

CAS: 138-14-7 Cat. No.: D409090 Molecular Weight: 656.79 EC Number: 205-314-3
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GRADE & PURITY 10mM in DMSO
Synonyms
Desferrioxamine B, DFOM, NSC 644468 | Butanediamide, N4-​[5-​[[4-​[[5-​(acetylhydroxyamino)​pentyl]​amino]​-​1,​4-​dioxobutyl]​hydroxyamino]​pentyl]​-​N1-​(5-​aminopentyl)​-​N1-​hydroxy-​, methanesulfonate (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
D409090-1ml
2
$36.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Deferoxamine mesylate (Ba 33112) Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabil
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥97%

Specifications

Synonyms
Desferrioxamine B, DFOM, NSC 644468 | Butanediamide, N4-​[5-​[[4-​[[5-​(acetylhydroxyamino)​pentyl]​amino]​-​1, ​4-​dioxobutyl]​hydroxyamino]​pentyl]​-​N1-​(5-​aminopentyl)​-​N1-​hydroxy-​, methanesulfonate (1:1)
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468) is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent. Deferoxamine is a ferroptosis inhibitor that stabilizes HIF-1α expression and improves
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
CHELATING AGENT
Mechanism of action
Iron chelating agent
Names and Identifiers
Isomeric SMILES CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
Molecular Weight 656.79
Reaxy-Rn 4122177
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4122177&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Citations of This Product
References
1. Tianyi Wu, Yun Teng, Dawei Song, Yuqi Yang, Huaishuang Shen, Xiao Sun, Rui Chen, Leyu Zhao, Xianggu Zhong, Qi Yan, Junjie Niu, Jun Ge, Liang Cheng, Jun Zou.  (2025)  A strategy targeting ferroptosis for mitochondrial reprogramming and intervertebral disc degeneration therapy.  Theranostics,  15  (17): (9159).  [PMID:40963903] [10.7150/thno.117725]
2. Shichen Zhang, Lei Guo, Yixin Tang, Yixing Wang, Heshi Liu, Chang Liu, Xiuzhang Yan, Congcong Duan, Huanyan Dai, Bing Han, Caina Xu.  (2025)  Self-reinforced nanoreactor for apoptosis/ferroptosis synergistic therapy of head and neck squamous cell carcinoma.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.166941]
3. Lu Hui, Fu Wenying, Xia Yiqun, Yan Ying, Shu Chongchong, Chen Yinghua, Xu Chenxin, Zheng Peisen, Shen Xin, Cui Ri, Zou Peng, Ni Daoyong.  (2025)  Panobinostat potentiates adagrasib-induced cell death by triggering autophagy in human non-small cell lung cancer.  Cell Death Discovery,  11  (1): (1-16).  [PMID:40750601] [10.1038/s41420-025-02657-9]
4. Wang Shengmei, Guo Qiuyan, Xu Rubing, Lin Peng, Deng Guoyan, Xia Xinhua.  (2023)  Combination of ferroptosis and pyroptosis dual induction by triptolide nano-MOFs for immunotherapy of Melanoma.  JOURNAL OF NANOBIOTECHNOLOGY,  21  (1): (1-21).  [PMID:37858186] [10.1186/s12951-023-02146-0]
5. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li.  (2023)  A potent GPX4 degrader to induce ferroptosis in HT1080 cells.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,      [PMID:38194774] [10.1016/j.ejmech.2023.116110]
6. Weimin Yin, Jiao Chang, Jiuyuan Sun, Yuge Zhao, Shiyu Chen, Hui Zhi, Jie Zang, Tingting Zhang, Yongyong Li, Haiqing Dong.  (2023)  Arginine nanoparticles mediated closed-loop ferroptosis enhancement for T cell activity boosting in cancer immunotherapy.  Applied Materials Today,      [PMID:] [10.1016/j.apmt.2023.102047]
7. Shan Gao, Wanlin Zhang, Xingxing Zhai, Xue Zhao, Jianxin Wang, Jie Weng, Jianshu Li, Xingyu Chen.  (2022)  An antibacterial and proangiogenic double-layer drug-loaded microneedle patch for accelerating diabetic wound healing.  Biomaterials Science,  11  (2): (533-541).  [PMID:36472206] [10.1039/D2BM01588A]
8. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang.  (2022)  Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment.  Acta Biomaterialia,      [PMID:35724919] [10.1016/j.actbio.2022.06.026]
9. Xueyang Jin, Ming Zhang, Jinghui Lu, Ximeng Duan, Jinyao Chen, Yue Liu, Wenqiang Chang, Hongxiang Lou.  (2021)  Hinokitiol chelates intracellular iron to retard fungal growth by disturbing mitochondrial respiration.  Journal of Advanced Research,      [PMID:35024181] [10.1016/j.jare.2021.06.016]
10. Fanjia Dai, Jiaying Zhang, Fengjiao Chen, Xianwu Chen, Celine Jessica Lee, Hongze Liang, Lingling Zhao, Hui Tan.  (2024)  A Multi-Responsive Hydrogel Combined With Mild Heat Stimulation Promotes Diabetic Wound Healing by Regulating Inflammatory and Enhancing Angiogenesis.  Advanced Science,      [PMID:39435670] [10.1002/advs.202408783]
11. Yupei Sun, Qin Lu, Die Dong, Rimei Chen, Zhiping Chen, Zhen Xie, Hongxiang Zhu, Qing Bu, Hui He, Shuangfei Wang.  (2024)  Engineering a monitoring-therapeutic in situ hydrogel via a cellulose-integrated nanointerface.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.149015]
12. Wajiha Ahmed, Shifen Li, Min Liang, Yongyuan Kang, Xiaoqing Liu, Changyou Gao.  (2024)  Multifunctional Drug- and AuNRs-Loaded ROS-Responsive Selenium-Containing Polyurethane Nanofibers for Smart Wound Healing.  ACS Biomaterials Science & Engineering,      [PMID:38701357] [10.1021/acsbiomaterials.4c00363]
13. Weichen Sun, Xiaoting Zuo, Yu Zhang, Chengyan Zhou, Shuai Guo, Wenjuan Li, Mingtao Run, Jianglei Qin.  (2024)  Quaternary ammonium grafted chitosan hydrogel with enhanced antibacterial performance as tannin acid and deferoxamine carrier to promote diabetic wound healing.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:39142232] [10.1016/j.colsurfb.2024.114160]
14. Huanghe Zeng, Lingling Tang, Li Huang, Na Yang, Xingyue Chen, Xi Peng, Zhengxian Chen, Jianxiu Guo, Jie Weng, Tailin Guo.  (2025)  A novel multi-functional PVA- alginate hydrogel with dynamic bond crosslinking for infected wound repair.  CARBOHYDRATE POLYMERS,      [PMID:40409832] [10.1016/j.carbpol.2025.123636]
15. Zhou Hai-Meng, Liu Yi, Shi Feng, Qiu Hao-Wen, Li Le, Shu Qi-Peng, Liu Yu-Ying, Wang Bai-Qi, Gao Meng, Du Run-Lei, Ke Shao-Bo, Zhang Xiao-Dong.  (2025)  CLK2 Regulates the KEAP1/NRF2 and p53 Pathways to Suppress Ferroptosis in Colorectal Cancer.  CANCER RESEARCH,      [PMID:40882016] [10.1158/0008-5472.CAN-24-4949]
16. Weijian Fan, Zebin Fang, Yuxiang Weng, Tianxiang Zhan, Kaiyuan Huang, Jianwei Pan, Renya Zhan.  (2025)  Iron enhances reactive oxygen species generation and initiates neutrophil extracellular traps formation on the endothelium to exacerbate stroke.  Journal of Cell Communication and Signaling,  19  (4): (e70050).  [PMID:41050264] [10.1002/ccs3.70050]
17. Wang Rong, Tian Xiao-Li, Li Jin, Chen Jia-Jia, Hu Yue, Zhang Ji.  (2026)  Ferrocene-contained cationic lipids via Ugi reaction for gene delivery and tumor cell ferroptosis.  JOURNAL OF MATERIALS SCIENCE,      [PMID:] [10.1007/s10853-026-12175-3]
18. Wen-tao Du, Ya-ru Wei, Xue Zhao, Qiang-qiang Gou, Omer Hassan Ali, Wen-di Wang, Jia-nan Xu, Zai-ping Feng, Xin-guo Zhang.  (2026)  Efficient Biosynthesis of Selenium-Enriched Saccharomyces cerevisiae via Siderophore-Assisted selenite uptake and biotransformation.  BIORESOURCE TECHNOLOGY,      [PMID:41638589] [10.1016/j.biortech.2026.134145]
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