Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Fadrozole (CGS16949A) Fadrozole (CGS16949A) is a potent, selective, nonsteroidal inhibitor of aromatase with an IC50 of 4.5 nM and selectivity over other cytochrome P-450 enzymes.
Targets
Aromatase 4.5 nM
| ALogP | 2.271 |
|---|---|
| hba_count | 1 |
| Rotatable Bond | 1 |
| Pubchem Sid | 504753697 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504753697 |
| Canonical Smiles | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
| IUPAC Name | 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile |
| InChIKey | CLPFFLWZZBQMAO-UHFFFAOYSA-N |
| INCHI | 1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2 |
| Isomeric SMILES | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
| Molecular Weight | 223.27 |
| Reaxy-Rn | 4294957 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4294957&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Imidazopyridines |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Imidazopyridines |
| Alternative Parents | Benzonitriles N-substituted imidazoles Heteroaromatic compounds Nitriles Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Imidazopyridine - Benzonitrile - Monocyclic benzene moiety - N-substituted imidazole - Benzenoid - Azole - Imidazole - Heteroaromatic compound - Carbonitrile - Nitrile - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as imidazopyridines. These are organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2212601 | Certificate of Analysis | Aug 18, 2025 | F414418 |
| K2212594 | Certificate of Analysis | Aug 18, 2025 | F414418 |
| K2212546 | Certificate of Analysis | Aug 18, 2025 | F414418 |
| K2212545 | Certificate of Analysis | Aug 18, 2025 | F414418 |
| D2410448 | Certificate of Analysis | Mar 23, 2024 | F414418 |
| D2410450 | Certificate of Analysis | Mar 23, 2024 | F414418 |
| D2410451 | Certificate of Analysis | Mar 23, 2024 | F414418 |
| D2410452 | Certificate of Analysis | Mar 23, 2024 | F414418 |
| F2516067 | Certificate of Analysis | Mar 23, 2024 | F414418 |
| C2411008 | Certificate of Analysis | Jul 05, 2022 | F414418 |
| K2212599 | Certificate of Analysis | Jul 05, 2022 | F414418 |
| Solubility | Solubility (25°C) In vitro DMSO: 45 mg/mL (201.54 mM); Ethanol: 45 mg/mL (201.54 mM); Water: Insoluble; |
|---|---|
| Sensitivity | Hygroscopic |
| DMSO(mg / mL) Max Solubility | 45 |
| DMSO(mM) Max Solubility | 201.549693196578 |
| Water(mg / mL) Max Solubility | ＜1 |
| Molecular Weight | 223.270 g/mol |
| XLogP3 | 2.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 223.111 Da |
| Monoisotopic Mass | 223.111 Da |
| Topological Polar Surface Area | 41.600 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 311.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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