Famciclovir - Moligand™, 10mM in DMSO , Human herpesvirus 1 DNA polymerase inhibitor, CAS No.104227-87-4, Human herpesvirus 1 DNA polymerase inhibitor

CAS: 104227-87-4 Cat. No.: F408994 Molecular Weight: 321.33 EC Number: 630-411-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

BRL-42810 | 2-​[2-​(2-​amino-​9H-​purin-​9-​yl)​ethyl]​-1,​3-​propanediol 1,​3-​diacetate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.
In vitro

In vivo

Cell Data

cell lines：KYSE-520 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

BRL-42810 | 2-​[2-​(2-​amino-​9H-​purin-​9-​yl)​ethyl]​-1, ​3-​propanediol 1, ​3-​diacetate

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Human herpesvirus 1 DNA polymerase inhibitor

Names and Identifiers

• Isomeric SMILES: CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
• WGK Germany: 3
• RTECS: TY3164000
• Molecular Weight: 321.33
• Reaxy-Rn: 4208403
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4208403&ln=

Chemical and Physical Properties

• Melt Point(°C): 105 °C

References

1. Tiemei Li, Lichong Duan, Mengmeng Du, Longrui Shi, Wenjuan Zhu, Chen Wang, Jing Fan.  (2023)  Hydrophobic deep eutectic solvent-based vortex assisted liquid–liquid microextraction for the determination of famciclovir in water samples coupled with high performance liquid chromatography.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.109697]

2. Zhipeng Zhang, Huizi Zheng, Ying Liu, Shuang Ma, Qi Feng, Jiao Qu, Xiaolin Zhu.  (2024)  Highly sensitive detection of multiple antiviral drugs using graphitized hydroxylated multi-walled carbon nanotubes/ionic liquids-based electrochemical sensors.  ENVIRONMENTAL RESEARCH,      [PMID:38354882] [10.1016/j.envres.2024.118466]