Galanthaminone - ≥98% , CAS No.510-77-0

CAS: 510-77-0 Cat. No.: G344638 Molecular Weight: 285.34 EC Number: 610-608-3
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
(4aS,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-one | 3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-one | Narwedine, (+/-)- | rel-(4aR,8aR)-3-Methoxy-11-methyl-4a,5,9,10
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
G344638-5mg
3

$153.90

$230.90
Save $77.00 (33.35%)
10mg
G344638-10mg
3

$214.90

$322.90
Save $108.00 (33.45%)
25mg
G344638-25mg
2

$469.90

$704.90
Save $235.00 (33.34%)
50mg
G344638-50mg
2

$613.90

$920.90
Save $307.00 (33.34%)
100mg
G344638-100mg
2

$1,039.90

$1,559.90
Save $520.00 (33.34%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

A metabolite of Galanthamine and a selective acetylcholinesterase inhibitor.

Specifications

Synonyms
(4aS, 8aS)-3-methoxy-11-methyl-4a, 5, 9, 10, 11, 12-hexahydro-6H-benzo[2, 3]benzofuro[4, 3-cd]azepin-6-one | 3-Methoxy-11-methyl-4a, 5, 9, 10, 11, 12-hexahydro-6H-benzo[2, 3]benzofuro[4, 3-cd]azepin-6-one | Narwedine, (+/-)- | rel-(4aR, 8aR)-3-Methoxy-11-methyl-4a, 5, 9, 10
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid504765415
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504765415
Canonical SmilesCN1CCC23C=CC(=O)CC2OC4=C(C=CC(=C34)C1)OC
IUPAC Name(1S,12S)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-one
InChIKeyQENVUHCAYXAROT-YOEHRIQHSA-N
INCHI1S/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/m0/s1
Isomeric SMILES CN1CC[C@@]23C=CC(=O)C[C@@H]2OC4=C(C=CC(=C34)C1)OC
Molecular Weight 285.34
Reaxy-Rn 1088844
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1088844&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassAlkaloids and derivatives
ClassAmaryllidaceae alkaloids
SubclassGalanthamine-type amaryllidaceae alkaloids
Intermediate Tree Nodes Not available
Direct ParentGalanthamine-type amaryllidaceae alkaloids
Alternative Parents Benzazepines  Coumarans  Anisoles  Cyclohexenones  Azepines  Aralkylamines  Alkyl aryl ethers  Trialkylamines  Oxacyclic compounds  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Galanthamine-type amaryllidaceae alkaloid - Benzazepine - Coumaran - Anisole - Alkyl aryl ether - Azepine - Cyclohexenone - Aralkylamine - Benzenoid - Ketone - Tertiary amine - Tertiary aliphatic amine - Cyclic ketone - Ether - Oxacycle - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Organopnictogen compound - Organooxygen compound - Amine - Organic oxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as galanthamine-type amaryllidaceae alkaloids. These are amaryllidaceae alkaloids with a structure characterized a tetracyclic skeleton with two ortho aromatic protons in ring A.
External Descriptors Isoquinoline alkaloids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
G-361 (890 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BJ (6930 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
K2209513Certificate of AnalysisAug 12, 2025 G344638
K2209514Certificate of AnalysisAug 12, 2025 G344638
K2209515Certificate of AnalysisAug 12, 2025 G344638
K2209516Certificate of AnalysisAug 12, 2025 G344638
K2209517Certificate of AnalysisAug 12, 2025 G344638
Chemical and Physical Properties
SolubilitySoluble in chloroform and DMSO.
Melt Point(°C)182-184°C (lit.)
Molecular Weight285.340 g/mol
XLogP31.700
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass285.136 Da
Monoisotopic Mass285.136 Da
Topological Polar Surface Area38.800 Ų
Heavy Atom Count21
Formal Charge0
Complexity477.000
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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