≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
GW 284543 hydrochloride (UNC 10225170) is a selective inhibitor of MEK5.
| Canonical Smiles | COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4.Cl |
|---|---|
| IUPAC Name | 6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine;hydrochloride |
| InChIKey | JUBMXFSNRBUGQI-UHFFFAOYSA-N |
| INCHI | 1S/C23H20N2O3.ClH/c1-26-22-14-19-20(11-12-24-21(19)15-23(22)27-2)25-16-7-6-10-18(13-16)28-17-8-4-3-5-9-17;/h3-15H,1-2H3,(H,24,25);1H |
| Isomeric SMILES | COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4.Cl |
| Molecular Weight | 408.9 |
| Reaxy-Rn | 24761613 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24761613&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Diphenylethers |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Diphenylethers |
| Alternative Parents | Diarylethers 4-aminoquinolines Phenoxy compounds Anisoles Aniline and substituted anilines Aminopyridines and derivatives Alkyl aryl ethers Primary aromatic amines Heteroaromatic compounds Secondary amines Azacyclic compounds Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Diphenylether - Aminoquinoline - Diaryl ether - 4-aminoquinoline - Quinoline - Anisole - Aniline or substituted anilines - Phenoxy compound - Phenol ether - Aminopyridine - Alkyl aryl ether - Primary aromatic amine - Pyridine - Heteroaromatic compound - Azacycle - Ether - Organoheterocyclic compound - Secondary amine - Amine - Hydrochloride - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as diphenylethers. These are aromatic compounds containing two benzene rings linked to each other through an ether group. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 A2416423 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416424 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416425 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416426 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416427 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416428 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416429 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| A2416430 | Certificate of Analysis | Dec 13, 2023 | G412520 |
| Molecular Weight | 408.900 g/mol |
|---|---|
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 408.124 Da |
| Monoisotopic Mass | 408.124 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 471.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
