H-Gly-Pro-AMC · HBr, CAS No.115035-46-6

CAS: 115035-46-6 Cat. No.: G342212 Molecular Weight: 410.26 EC Number: 823-565-2

GRADE & PURITY ≥95%

Overview

GP-AMC, Fluorogenic Substrate is a substrate with an excitation at 380 nm and emission at 460 nm. The substrate has been used to study the activity of CD26 (DPIV and DPPIV), DPP7 (DPPII/VII) , DPRP1 (DPP8), DPRP2 (DPP9), FAP (fibroblast activation protein), and POP/PREP. The compound has been used in a peptide assay where the release of AMC was monitored as well as in|in vitro|inhibtior screening.

Specifications

Product Name

H-Gly-Pro-AMC · HBr, CAS No.115035-46-6

Synonyms

Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide

Specifications & Purity

≥95%

Sequence

H-Gly-Pro-7-amino-4-methylcoumarin

CAS

115035-46-6

Molecule Type

Peptide

Storage and Shipping

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: Proline and derivatives Alpha amino acid amides Coumarins and derivatives 1-benzopyrans Pyrrolidinecarboxamides N-arylamides N-acylpyrrolidines Pyranones and derivatives Benzenoids Tertiary carboxylic acid amides Heteroaromatic compounds Secondary carboxylic acid amides Lactones Oxacyclic compounds Azacyclic compounds Carbonyl compounds Hydrobromides Hydrocarbon derivatives Monoalkylamines Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-dipeptide - Proline or derivatives - Alpha-amino acid amide - Coumarin - 1-benzopyran - Alpha-amino acid or derivatives - Benzopyran - N-acylpyrrolidine - Pyrrolidine carboxylic acid or derivatives - N-arylamide - Pyrrolidine-2-carboxamide - Pyranone - Pyran - Benzenoid - Pyrrolidine - Heteroaromatic compound - Tertiary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Lactone - Secondary carboxylic acid amide - Oxacycle - Azacycle - Organoheterocyclic compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Amine - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organic oxide - Hydrobromide - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y