H-Lys(Boc)-OH - ≥97% , CAS No.2418-95-3

CAS: 2418-95-3 Cat. No.: L110998 Molecular Weight: 246.3 Beilstein Registry Number: 2417626 EC Number: 690-500-0

GRADE & PURITY ≥97%

Synonyms

MFCD00037221 | J-300183 | N6-(tert-butoxycarbonyl)-L-lysine | Nepsilon -(tert-butoxycarbonyl)-L-lysine | Lys(Boc) | LBY | Nepsilon-t-Butoxycarbonyl-L-lysine | AKOS015924115 | H-Lys(Boc)-OH, >=95% | Ne-Boc-L-lysine | (S)-2-Amino-6-((tert-butoxycarbonyl)ami

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Application：

Nε-Boc-D-lysine is an N-Boc-protected form of L-Lysine (L468895).L-Lysine can be found in a variety of food, such as eggs and quinoa, but is also mass produced by microbial fermentation. L-Lysine is also used as therapy to treat recurrent herpes simplex infections. 

Specifications

Synonyms

MFCD00037221 | J-300183 | N6-(tert-butoxycarbonyl)-L-lysine | Nepsilon -(tert-butoxycarbonyl)-L-lysine | Lys(Boc) | LBY | Nepsilon-t-Butoxycarbonyl-L-lysine | AKOS015924115 | H-Lys(Boc)-OH, >=95% | Ne-Boc-L-lysine | (S)-2-Amino-6-((tert-butoxycarbonyl)ami

Specifications & Purity

≥97%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 504760985
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760985
• Canonical Smiles: CC(C)(C)OC(=O)NCCCCC(C(=O)O)N
• IUPAC Name: (2S)-2-amino-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
• InChIKey: VVQIIIAZJXTLRE-QMMMGPOBSA-N
• INCHI: 1S/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
• Isomeric SMILES: CC(C)(C)OC(=O)NCCCC[C@@H](C(=O)O)N
• WGK Germany: 3
• Molecular Weight: 246.3
• Beilstein: 2417626
• Reaxy-Rn: 2417626
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2417626&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Medium-chain fatty acids Branched fatty acids Amino fatty acids Carbamate esters Organic carbonic acids and derivatives Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Branched fatty acid - Fatty acyl - Fatty acid - Carbamic acid ester - Carbonic acid derivative - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Amine - Primary aliphatic amine - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Slightly soluble in water.
• Specific Rotation[α]: 18 ° (C=1, AcOH)
• Melt Point(°C): 250°C
• Molecular Weight: 246.300 g/mol
• XLogP3: -1.600
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 246.158 Da
• Monoisotopic Mass: 246.158 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 261.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xiaodan Wang, Fangping Yang, Huawei Yang, Xu Zhang, Haoyu Tang, Shifang Luan.  (2021)  Preparation of antibacterial polypeptides with different topologies and their antibacterial properties.  Biomaterials Science,  10  (3): (834-845).  [PMID:35005755] [10.1039/D1BM01620B]

2. Chen Chao, Yu Guiling, Huang Yujia, Cheng Wenhui, Li Yuxuan, Sun Yi, Ye Haifeng, Liu Tao.  (2021)  Genetic-code-expanded cell-based therapy for treating diabetes in mice.  Nature Chemical Biology,  18  (1): (47-55).  [PMID:34782743] [10.1038/s41589-021-00899-z]