H-Lys(Fmoc)-OMe HCl - ≥98% , CAS No.201009-98-5

CAS: 201009-98-5 Cat. No.: H182558 Molecular Weight: 418.9

GRADE & PURITY ≥98%

Synonyms

AKOS016010330 | L-Lysine,n6-[(9H-fluoren-9-ylmethoxy)carbonyl]-,methyl ester,monohydrochloride(9ci) | Methyl N6-(((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysinate hydrochloride | Methyl N~6~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysinate--hydrogen chloride

Storage

Room temperature

Shipped In

Normal

Specifications

Synonyms

AKOS016010330 | L-Lysine, n6-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester, monohydrochloride(9ci) | Methyl N6-(((9H-fluoren-9-yl)methoxy)carbonyl)-L-lysinate hydrochloride | Methyl N~6~-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysinate--hydrogen chloride

Specifications & Purity

≥98%

Storage

Room temperature

Shipped In

Normal

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488201753
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488201753
• Canonical Smiles: COC(=O)C(CCCCNC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)N.Cl
• IUPAC Name: methyl (2S)-2-amino-6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoate;hydrochloride
• InChIKey: KKSJCURWQOUTKB-BDQAORGHSA-N
• INCHI: 1S/C22H26N2O4.ClH/c1-27-21(25)20(23)12-6-7-13-24-22(26)28-14-19-17-10-4-2-8-15(17)16-9-3-5-11-18(16)19;/h2-5,8-11,19-20H,6-7,12-14,23H2,1H3,(H,24,26);1H/t20-;/m0./s1
• Isomeric SMILES: COC(=O)[C@H](CCCCNC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)N.Cl
• Molecular Weight: 418.9
• Reaxy-Rn: 23336672
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23336672&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Fluorenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Fluorenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Fluorenes
• Alternative Parents: Alpha amino acid esters Fatty acid esters Methyl esters Carbamate esters Monocarboxylic acids and derivatives Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Alpha-amino acid ester - Fluorene - Alpha-amino acid or derivatives - Fatty acid ester - Fatty acyl - Methyl ester - Carbamic acid ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organic oxygen compound - Primary aliphatic amine - Primary amine - Hydrochloride - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Amine - Organonitrogen compound - Organooxygen compound - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 418.900 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Exact Mass: 418.166 Da
• Monoisotopic Mass: 418.166 Da
• Topological Polar Surface Area: 90.700 Ų
• Heavy Atom Count: 29
• Formal Charge: 0
• Complexity: 505.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Xiaolei Ma, Rui Cong, Xin Cui, Yiwei Tang, Jie Ren, Jinfan Hou, Boyu Liu, Jiehui Zhao, Pengwei Li, Lei Li, Heyang Zhang, Jiasheng Tu, Lei Jiang.  (2025)  Dendritic lipopeptide based transdermal siRNA delivery systems for effective non-invasive therapy in psoriasis.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40020928] [10.1016/j.jconrel.2025.113581]