H-Val-Gly-OH - ≥95% , CAS No.686-43-1

CAS: 686-43-1 Cat. No.: B301365 Molecular Weight: 174.2

GRADE & PURITY ≥95%

Synonyms

HMS1535G10 | 2-[(2S)-2-amino-3-methylbutanamido]acetic acid | CHEBI:73699 | Q27143863 | H-VAL-GLY-OH | BDBM50407444 | SCHEMBL2782029 | GLYCINE, N-DL-VALYL- | L-Val-Gly | (S)-2-(2-Amino-3-methylbutanamido)acetic acid | V-G | L-Valylglycine | L-valyl-glycin

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Val-Gly is a dipeptide formed from L-valine and glycine residues. It has a role as a metabolite. It derives from a L-valine and a glycine. It is a tautomer of a Val-Gly zwitterion.

Specifications

Synonyms

HMS1535G10 | 2-[(2S)-2-amino-3-methylbutanamido]acetic acid | CHEBI:73699 | Q27143863 | H-VAL-GLY-OH | BDBM50407444 | SCHEMBL2782029 | GLYCINE, N-DL-VALYL- | L-Val-Gly | (S)-2-(2-Amino-3-methylbutanamido)acetic acid | V-G | L-Valylglycine | L-valyl-glycin

Specifications & Purity

≥95%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504764441
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764441
• Canonical Smiles: CC(C)C(C(=O)NCC(=O)O)N
• IUPAC Name: 2-[[(2S)-2-amino-3-methylbutanoyl]amino]acetic acid
• InChIKey: IOUPEELXVYPCPG-LURJTMIESA-N
• INCHI: 1S/C7H14N2O3/c1-4(2)6(8)7(12)9-3-5(10)11/h4,6H,3,8H2,1-2H3,(H,9,12)(H,10,11)/t6-/m0/s1
• Isomeric SMILES: CC(C)[C@@H](C(=O)NCC(=O)O)N
• Molecular Weight: 174.2
• Reaxy-Rn: 1724724
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724724&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: Valine and derivatives N-acyl-alpha amino acids Alpha amino acid amides N-acyl amines Secondary carboxylic acid amides Amino acids Carboxylic acid salts Carboxylic acids Monocarboxylic acids and derivatives Monoalkylamines Hydrocarbon derivatives Organopnictogen compounds Organic salts Carbonyl compounds Organic zwitterions Organic oxides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-dipeptide - Valine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Alpha-amino acid or derivatives - Fatty acyl - Fatty amide - N-acyl-amine - Amino acid or derivatives - Carboxamide group - Amino acid - Carboxylic acid salt - Secondary carboxylic acid amide - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Primary aliphatic amine - Organic zwitterion - Organic salt - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Amine - Organic oxygen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: dipeptide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ACE Tclin Angiotensin-converting enzyme (1423 Activities)

Discover Target: ACE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: air sensitive；heat sensitive
• Molecular Weight: 174.200 g/mol
• XLogP3: -2.700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 174.1 Da
• Monoisotopic Mass: 174.1 Da
• Topological Polar Surface Area: 92.400 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 179.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xiaoyu Zhang, Shun Zhou, Jin Zhang, Jiuyi Liu, Xiaofeng Wang, Weijian Chen, Yanyan Li, Mengdie Cai, Lisheng Guo, Song Sun.  (2025)  Effects of different heating methods on pyrolysis and smoke release characteristics of tobacco granules.  JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS,      [PMID:] [10.1016/j.jaap.2025.107099]